118535-73-2Relevant articles and documents
Al Lewis acid-catalyzed regiodivergent 1,2-rearrangement of α-siloxy aldehydes: scope and mechanism
Ohmatsu, Kohsuke,Tanaka, Takayuki,Ooi, Takashi,Maruoka, Keiji
experimental part, p. 7516 - 7522 (2009/12/04)
Regiodivergent 1,2-rearrangement of α-siloxy aldehydes bearing α-aryl and α-alkyl substituents into α-siloxy ketones has been realized by using different Al Lewis acid catalyst/solvent systems. The scope of this unprecedented protocol has been investigate
Complete switch of migratory aptitude in aluminum-catalyzed 1,2-rearrangement of differently α,α-disubstituted a-siloxy aldehydes
Ohmatsu, Kohsuke,Tanaka, Takayuki,Ooi, Takashi,Maruoka, Keiji
supporting information; experimental part, p. 5203 - 5206 (2009/04/11)
(Chemical Equation Presented) Control of the migration tendency: The regiodivergent 1,2-rearrangement of asiloxy aldehydes bearing α-aryl and α-alkyl substituents into α-siloxy ketones has been realized by using different aluminum Lewis acid catalyst/solvent systems (see scheme). The scope of this unprecedented protocol has been investigated with various substrates and clearly demonstrates its utility for the selective synthesis of two structural isomers from one substrate.
ENANTIOSELECTIVE SYNTHESIS OF PROTECTED α-HYDROXY ALDEHYDES AND KETONES VIA HYDROXYLATION OF METALATED CHIRAL HYDRAZONES
Enders, Dieter,Bhushan, Vidya
, p. 2437 - 2440 (2007/10/02)
α-Benzyloxy aldehydes and α-acetoxy ketones 4 of high enantiomeric purity are prepared in good overall yields via oxaziridine mediated hydroxylation of chiral hydrazone azaenolates.As auxiliaries novel proline derived hydrazine reagents 5 are used.