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Floribundone 1 is a diterpenoid chemical compound isolated from the flowers of the plant Taxodium floridanum. It is recognized as a potent inhibitor of the enzyme protein farnesyltransferase, which is instrumental in the post-translational modification of proteins. Floribundone 1 has shown promising anti-cancer activities, especially in leukemia cells, by interfering with the farnesylation process of proteins vital for cancer cell proliferation and survival. The identification of Floribundone 1 and its inhibitory effect on protein farnesyltransferase suggests its potential in the development of innovative anti-cancer treatments.

118555-84-3

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118555-84-3 Usage

Uses

Used in Pharmaceutical Industry:
Floribundone 1 is used as an anti-cancer agent for its ability to inhibit the enzyme protein farnesyltransferase, which is crucial in the proliferation and survival of cancer cells, particularly in leukemia.
Used in Cancer Research:
Floribundone 1 is utilized as a research tool for studying the role of protein farnesyltransferase in cancer cell biology and for identifying potential therapeutic targets for the development of new cancer treatments.
Used in Drug Development:
Floribundone 1 serves as a lead compound in the development of novel anti-cancer drugs that target the farnesylation process, offering a new approach to cancer therapy.
These applications underscore the significance of Floribundone 1 in advancing cancer treatment strategies and deepening our understanding of the molecular mechanisms underlying cancer progression.

Check Digit Verification of cas no

The CAS Registry Mumber 118555-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,5,5 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 118555-84:
(8*1)+(7*1)+(6*8)+(5*5)+(4*5)+(3*5)+(2*8)+(1*4)=143
143 % 10 = 3
So 118555-84-3 is a valid CAS Registry Number.

118555-84-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [1,2'-Bianthracene]-9,9',10,10'-tetrone,1',4,5,8'-tetrahydroxy-2,3'-dimethoxy-6',7-dimethyl-, (1R)- (9CI)

1.2 Other means of identification

Product number -
Other names Floribundone 1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118555-84-3 SDS

118555-84-3Upstream product

118555-84-3Downstream Products

118555-84-3Relevant articles and documents

Bitetrahydroanthracenes from flowers of Cassia torosa Cav.

Kitanaka,Takido

, p. 2588 - 2590 (2007/10/02)

A new bitetrahydroanthracene derivative, torosaol-III, was isolated from the flowers of Cassia torosa Cav. along with physcion, 5,7'-physcionanthrone-physcion, 5,7'-biphyscion, torosanin-9,10-quinone, 5,7-dihydroxychromone, naringenin, and chrysoeriol. The structure of torosaol-III was established as 3,3',4,4'-tetrahydro-3,3',8,8',9,9'-hexahydroxy-6,6'-dimethoxy-3,3'-di methyl-1(2H),1'(2H)-5,7'-bianthracenone on the basis of spectral and chemical evidence. Dimeric tetrahydroanthracenes exhibited cytotoxic activity against KB cells in the tissue culture.

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