118584-90-0

Basic information

• Product Name: FMOC-L-LYS(DANSYL)-OH
• Synonyms: FMOC-L-LYS(DANSYL)-OH;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-DANSYL-L-LYSINE;N-(9-Fluorenylmethyloxycarbonyl)-N'-dansyl-L-lysine;N-Fmoc-N'-dansyl-L-lysine;Fmoc-Lys(dansyl)-OH;Nα-Fmoc-Nε-dansyl-L-lysine≥ 97% (HPLC);(9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Dansyl)-OH;(2S)-6-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
• CAS NO: 118584-90-0
• Molecular Formula: C33H35N3O6S
• Molecular Weight: 601.71
• Mol File: 118584-90-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: FMOC-L-LYS(DANSYL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-L-LYS(DANSYL)-OH(118584-90-0)
• EPA Substance Registry System: FMOC-L-LYS(DANSYL)-OH(118584-90-0)

Safety Data

• Hazardous Substances Data: 118584-90-0(Hazardous Substances Data)

Usage

Uses

Used in Biochemistry Research:
FMOC-L-LYS(DANSYL)-OH is used as a substrate for fluorometric proteolytic enzyme assays, providing a means to study enzyme kinetics, specificity, and activity. The dansyl group's fluorescence allows for the real-time monitoring of enzymatic reactions, offering a sensitive and quantitative approach to enzyme analysis.
Used in Drug Discovery and Development:
In the pharmaceutical industry, FMOC-L-LYS(DANSYL)-OH can be employed as a tool for the identification and optimization of potential drug candidates targeting proteolytic enzymes. By monitoring the fluorescence changes upon enzyme cleavage, researchers can screen for compounds that modulate enzyme activity, leading to the development of novel therapeutic agents.
Used in Diagnostic Applications:
FMOC-L-LYS(DANSYL)-OH can be utilized in the development of diagnostic assays for various diseases, particularly those involving abnormal proteolytic activity. The dansyl group's fluorescence can be harnessed to create sensitive and specific tests for the detection and monitoring of disease biomarkers, aiding in early diagnosis and treatment.
Used in Education and Training:
In academic settings, FMOC-L-LYS(DANSYL)-OH serves as an educational tool for teaching students about enzyme kinetics, mechanisms, and the principles of fluorescence-based assays. It provides a hands-on experience in conducting experiments and understanding the fundamental concepts of biochemistry and molecular biology.

Upstream product

• 605-65-2 5-(dimethylamino)naphth-1-ylsulfonyl chloride 
• 105047-45-8 Fmoc-Lys-OH 

Downstream Products

• 1435485-71-4 C₆₇H₈₅N₁₅O₉S 

Relevant articles and documents

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