1186015-85-9Relevant articles and documents
Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes
Kakadiya, Rajesh,Dong, Huajin,Lee, Pei-Chih,Kapuriya, Naval,Zhang, Xiuguo,Chou, Ting-Chao,Lee, Te-Chang,Kapuriya, Kalpana,Shah, Anamik,Su, Tsann-Long
, p. 5614 - 5626 (2009)
A series of bifunctional DNA interstrand cross-linking agents, bis(hydroxymethyl)- and bis(carbamates)-8H-3a-azacyclopenta[a]indene-1-yl derivatives were synthesized for antitumor evaluation. The preliminary antitumor studies revealed that these agents ex