1198074-93-9Relevant articles and documents
Synthesis of isoxazole conjugates of 1,4-benzodioxane moiety via intermolecular 1,3-dipolar cycloaddition
Vaidya, Vipraja V.,Wankhede, Karuna S.,Nara, Susheel J.,Salunkhe, Manikrao M.,Trivedi, Girish K.
, p. 3856 - 3866 (2009)
1,3-Dipolar cycloaddition was utilized as a tool to conjugate the 1,4-benzodioxane moiety with several biologically active compounds such as steroid, sugar, and other aromatic scaffolds via isoxazole or triazole bridge. The propynyl ether of 2-hydroxymethyl-1,4-benzodioxane underwent 1,3-dipolar cycloadditions smoothly with different in situ generated nitrile oxides in good yields. The triazole conjugate of 1,4-benzodioxane was synthesized via click chemistry. Copyright Taylor & Francis Group, LLC.