119916-22-2

Basic information

• Product Name: 2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID
• Synonyms: 2,4,5-Trifluoro-6-methylbenzoic acid;2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID;3-Methyl-2,4,5-trifluorobenzoyl chloride;3,4,6-Trifluoro-2-methylbenzoic Acid
• CAS NO: 119916-22-2
• Molecular Formula: C₈H₅F₃O₂
• Molecular Weight: 190.12
• Product Categories: Benzoic acid
• Mol File: 119916-22-2.mol

Chemical Properties

• Melting Point: 108-110℃
• Boiling Point: 256.2°Cat760mmHg
• Flash Point: 108.7°C
• Appearance: /
• Density: 1.452g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.492
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform; Ethyl Acetate; Methanol
• PKA: 2.59±0.37(Predicted)
• CAS DataBase Reference: 2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID(119916-22-2)
• EPA Substance Registry System: 2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID(119916-22-2)

Safety Data

• Hazardous Substances Data: 119916-22-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-METHYL-3,4,6-TRIFLUORO BENZOIC ACID is used as an intermediate in the synthesis of dl-Grepafloxacin (G783000) for its role in the development of antibacterial compounds. The compound contributes to the creation of effective treatments for various respiratory infections, showcasing its importance in the pharmaceutical sector.

InChI:InChI=1/C8H5F3O2/c1-3-6(8(12)13)4(9)2-5(10)7(3)11/h2H,1H3,(H,12,13)

Upstream product

• 327-52-6 1-bromo-2,4,5-trifluorobenzene 
• 446-17-3 2,4,5-trifluorobenzoic acid 
• 88419-56-1 2,4,5-trifluorobenzoyl chloride 
• 132630-85-4 1-bromo-2,4,5-trifluoro-6-methyl-3-(trimethylsilyl)benzene 
• 125290-72-4 2-(2,4,5-trifluorophenyl)-4,4-dimethyl-2-oxazoline 
• 125290-73-5 2-<2,4,5-trifluoro-3-(trimethylsilyl)phenyl>-4,4-dimethyl-2-oxazoline 
• 125290-74-6 2-<2,4,5-trifluoro-6-methyl-3-(trimethylsilyl)phenyl>-4,4-dimethyl-2-oxazoline 
• 132233-72-8 1-bromo-2,4,5-trifluoro-3-(trimethylsilyl)benzene 
• 142603-49-4 2,4,5-trifluoro-6-methylisophthalic acid 
• 57612-65-4 2,3,4,5-tetrafluoro-6-methylbenzoic acid 
• 32890-92-9 2,3,4,6-tetrafluorobenzoic acid 

Downstream Products

• 119915-41-2 2-methyl-3,4,6-trifluorobenzoyl chloride 
• 119916-38-0 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acid 
• 119915-47-8 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acid 
• 119915-44-5 ethyl α-(ethoxymethylene)-3,4,6-trifluoro-2-methyl-β-oxobenzenepropanoate 
• 119915-43-4 ethyl (2,4,5-trifluoro-6-methylbenzoyl)acetate 

Relevant articles and documents

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