1200-06-2

Basic information

• Product Name: Acetic acid p-methoxyphenyl ester
• Synonyms: 4-Methoxyphenol acetate;Acetic acid 4-methoxyphenyl ester;Acetic acid p-anisyl ester;Acetic acid p-methoxyphenyl ester;p-Acetoxyanisole;Phenol, 4-methoxy-,1-acetate
• CAS NO: 1200-06-2
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.1739
• Mol File: 1200-06-2.mol
• Article Data: 152

Chemical Properties

• Boiling Point: 246.1°Cat760mmHg
• Flash Point: 96.4°C
• Appearance: /
• Density: 1.099g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: Acetic acid p-methoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid p-methoxyphenyl ester(1200-06-2)
• EPA Substance Registry System: Acetic acid p-methoxyphenyl ester(1200-06-2)

Safety Data

• Hazardous Substances Data: 1200-06-2(Hazardous Substances Data)

Usage

General Description

Acetic acid p-methoxyphenyl ester, also known as p-methoxyphenyl acetate, is an organic chemical compound with the molecular formula C9H10O3. It is a colorless liquid with a fruity odor used as a fragrance and flavoring ingredient in various consumer products. It is also used as an intermediate in the synthesis of pharmaceuticals and as a solvent in organic synthesis. Acetic acid p-methoxyphenyl ester is known for its low toxicity and is generally considered safe for use in cosmetics and personal care products. However, it should be handled with care as it can cause irritation to the skin, eyes, and respiratory tract upon exposure.

Upstream product

• 100-66-3 methoxybenzene 
• 98-95-3 nitrobenzene 
• 150-76-5 4-methoxy-phenol 
• 75-36-5 acetyl chloride 
• 878-00-2 4-formylphenyl acetate 
• 29368-59-0 p-methoxyphenolate 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 935-50-2 4,4-dimethoxycyclohexa-2,5-dienone 
• 39652-02-3 bis(4-methoxyphenyl)-λ⁴-tellanediyl diacetate 
• 459-60-9 1-fluoro-4-methoxybenzene 
• 64-19-7 acetic acid 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 94-36-0 dibenzoyl peroxide 
• 127-08-2 potassium acetate 

Downstream Products

• 705-15-7 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 150-76-5 4-methoxy-phenol 
• 569343-14-2 1-(4-methoxyphenoxy)-1-(trimethylsiloxy)ethene 
• 1551217-34-5 C₂₄H₂₄N₄O₅ 
• 13252-84-1 4-hydroxy-6-methoxycoumarin 
• 1551217-31-2 C₁₈H₁₃N₃O₄ 
• 1551217-46-9 C₁₉H₁₄FN₃O₄ 
• 1551217-53-8 C₁₈H₁₂FN₃O₄ 
• 364360-13-4 2-amino-5-(4-methoxylphenoxymethyl)-1,3,4-thiadiazole 
• 3393-77-9 bis(4-methoxyphenyl)sulfide 
• 5633-57-8 1-methoxy-4-(phenylsulfanyl)benzene 
• 6013-47-4 4-methylphenyl 4-methoxyphenyl sulfide 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

Size-selective catalysts in five functionalized porous coordination polymers with unsaturated zinc centers

The five reported structural isomorphic porous coordination polymers (PCPs) 1-5, namely, [Zn(L)(ip) (1), Zn(L)(aip) (2), Zn(L)(hip) (3), Zn(L)(nip) (4), and Zn(L)(HBTC) (5) (L = N4,N4′-di(pyridine-4-yl)biphenyl-4,4′-dicarboxamide, H2ip = isophthalic acid, H2aip = 5-aminoisophthalic acid, H2hip = 5-hydroxyisophthalic acid, H2nip = 5-nitroisophthalic acid, H3BTC = 1,3,5-benzenetricarboxylic acid)] were used to catalyze the acetylation of phenol. All these heterogeneous catalysts exhibit good catalytic efficiency and size-selectivity toward the acetylation of phenols owing to their unsaturated metal centers, non-coordinated amide, and suitable channel size and shape. Among them, 2 displays the highest catalytic activity and excellent cooperative catalysis due to the presence of basic non-coordinated amide groups.

Structure-activity relationship on human serum paraoxonase (PON1) using substrate analogues and inhibitors

Substrate analogues based on the parent compounds paraoxon and phenyl acetate were tested on human serum paraoxonase (PON1) to explore the active site of the enzyme. Replacement of the nitro group of paraoxon with an amine or hydrogen, as well as electronic changes to the parent compound, converted these analogues into inhibitors. Introduction of either electron-withdrawing or donating groups onto phenyl acetate resulted in reduction in their rate of hydrolysis by PON1.

Proteinase K from the mold Tritirachium album Limber. Specificity and mode of action

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Use of Molecular Oxygen in the Baeyer-Villiger Oxidation The Influence of Metal Catalysts

Baeyer-Villiger oxidation of ketones using molecular oxygen and benzaldehyde in the absence of metal catalysts afforded lactones in high yields.The catalytic activity of various metal salts has been studied.Key Words: Baeyer-Villiger oxidation, Molecular

Electron-transfer Chain (ETC) Promotion of Aromatic Substitution Reactions. Entry into the SON2 Mechanism via Ipso Radical Attack

The oxidative electron-transfer chain mechanism, the SON2 mechanism, is shown to be initiated by benzoyl-oxyl radicals, since 4-fluoroanisole can be converted into a mixture of 4-methoxyphenyl acetate and benzoate (maximum ratio 10:1) in high yield by decomposing benzoyl peroxide in HOAc-KOAc at 78 deg C.

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Acetylation of phenols in organic solvent catalyzed by a lipase from chromobacterium viscosum

Lipase from Chromobacterium viscosum, absorbed on an inert support, was employed as catalyst for the esterification of monohydric phenols in organic solvent, with vinyl acetate as acyl donor. The effect of aromatic ring substitution on the initial rate of transesterification was investigated.

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Noncross-linked polystyrene nanoencapsulation of ferric chloride: A novel and reusable heterogeneous macromolecular Lewis acid catalyst toward selective acetylation of alcohols, phenols, amines, and thiols

Ferric chloride has been successfully nanoencapsulated for the first time on a non-cross-linked polystyrene matrix as the shell material via the coacervation technique. The resulting polystyrene nanoencapsulated ferric chloride was used as a novel and rec

Preparation process of 2-bromo-4-hydroxy anisole

The invention relates to a preparation process of 2-bromo-4-hydroxy anisole. The preparation process comprises the following steps: reacting 4-hydroxy anisole with acetyl chloride in an organic alkalisolution at low temperature to generate 4-acetyl anisol

Copper-Catalyzed Acetylation of Electron-Rich Phenols and Anilines

An approach has been developed for the copper-catalyzed acetylation of phenols and anilines with potassium thioacetate as an acetylating reagent. Although only electron-rich phenols and anilines are compatible with this protocol, the reaction can provide moderate to high yields under mild conditions. Compared with other acetylating reagents, the current reagent has certain advantages, such as its low cost, easy availability, stability, insensitivity to water or air, and ease of storage.