1202385-73-6Relevant articles and documents
Convenient, mild catalytic deprotection of oximes to carbonyl compounds with hydrogen peroxide and iodine catalyst in aqueous acetonitrile
Ganguly, Nemai C.,Nayek, Subhasis,Barik, Sujoy Kumar
, p. 4053 - 4061 (2009)
A clean, mild, and efficient catalytic deoximation procedure compatible with several common functional groups has been developed using 30% hydrogen peroxide activated by iodine catalyst in aqueous acetonitrile under essentially neutral conditions. The mechanistic features of an iodonium ion-driven nucleophilic cleavage of oximic C=N have been revealed.