1202769-66-1

Basic information

• Product Name: 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol
• Synonyms: 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol;2-(5-Methyl-1,2-Oxazol-3-Yl)But-3-Yn-2-Ol
• CAS NO: 1202769-66-1
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16256
• Mol File: 1202769-66-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 256.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.165±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.23±0.29(Predicted)
• CAS DataBase Reference: 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol(1202769-66-1)
• EPA Substance Registry System: 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol(1202769-66-1)

Safety Data

• Hazardous Substances Data: 1202769-66-1(Hazardous Substances Data)

Usage

General Description

2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol is a chemical compound with the molecular formula C9H9NO2. It is a derivative of isoxazole and contains a five-membered heterocyclic ring with a methyl group attached to the third position. The molecule also contains a butyn-3-ynyl group and an alcohol functional group. 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block for more complex molecules. It has also been studied for its potential pharmacological activities and biological effects.

Upstream product

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Relevant articles and documents

SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.

6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR

The invention relates to novel compounds of Formula I: wherein A, Y, R1, R2 and the subscript b each has the meaning as described herein and compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, isotopes, pharmaceutically acceptable salts, or prodrugs thereof. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.