120802-87-1Relevant articles and documents
Preparation of tertiary alkyl carbinamines, propargylamines, and α-heteroarylamines by ketone-based aminoalkylation
Katritzky, Alan R.,Yang, Hongfang,Singh, Sandeep K.
, p. 286 - 290 (2007/10/03)
(Chemical Equation Presented). Ketones 6a-i were converted into their benzotriazolylamine adducts 8a-i either directly from the corresponding ketone 6a or via enamines 7b-i. Adducts 8a-i on treatment with Grignard reagents, lithium phenylacetylide, or heteroaryllithiums gave tertiary alkyl carbinamines 9a-h (47-61%), propargylamines 10a-i (30-98%), and α-heteroarylamines 11a-k (44-85%), respectively.