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7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine is a chemical compound that belongs to the triazolopyridine class. It features a boron-containing ring structure and is recognized for its potential as a building block in the development of pharmaceutical and agrochemical compounds. 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine has garnered interest in medicinal chemistry due to its demonstrated antimicrobial and antitumor activities, along with its utility as a ligand in the synthesis of coordination polymers and metal-organic frameworks. Its distinctive structural and functional attributes render it a significant asset in both chemical and biological research.

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  • 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine

    Cas No: 1210048-18-2

  • USD $ 1.9-2.9 / Gram

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  • 1210048-18-2 Structure
  • Basic information

    1. Product Name: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine
    2. Synonyms: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine
    3. CAS NO:1210048-18-2
    4. Molecular Formula: C12H16BN3O2
    5. Molecular Weight: 245.08534
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1210048-18-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.19±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 2.48±0.30(Predicted)
    10. CAS DataBase Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(1210048-18-2)
    12. EPA Substance Registry System: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(1210048-18-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1210048-18-2(Hazardous Substances Data)

1210048-18-2 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine is utilized as a building block for the synthesis of various pharmaceutical and agrochemical compounds. Its incorporation into these products is attributed to its unique boron-containing ring structure, which can enhance the biological activity and selectivity of the final compounds.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine is employed as a compound with potential antimicrobial and antitumor properties. Its ability to target and inhibit the growth of harmful microorganisms and tumor cells makes it a promising candidate for the development of new therapeutic agents.
Used in the Synthesis of Coordination Polymers and Metal-Organic Frameworks:
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine also serves as a valuable ligand in the synthesis of coordination polymers and metal-organic frameworks. Its unique structural features allow for the creation of complex and functional materials with potential applications in areas such as catalysis, gas storage, and sensing.
Used in Chemical and Biological Research:
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine's distinctive properties make it a valuable tool for researchers in chemical and biological fields. Its ability to form various complexes and its potential biological activities provide a foundation for exploring new reactions, mechanisms, and applications in both academia and industry.

Check Digit Verification of cas no

The CAS Registry Mumber 1210048-18-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,0,0,4 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1210048-18:
(9*1)+(8*2)+(7*1)+(6*0)+(5*0)+(4*4)+(3*8)+(2*1)+(1*8)=82
82 % 10 = 2
So 1210048-18-2 is a valid CAS Registry Number.

1210048-18-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine

1.2 Other means of identification

Product number -
Other names 7-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1210048-18-2 SDS

1210048-18-2Relevant articles and documents

FUSED RING DERIVATIVE AS A2A RECEPTOR INHIBITOR

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Paragraph 0093-0096, (2020/08/09)

Disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and an application of the compound or slat in preparation of drugs for treating diseases related to an A2A receptor.

SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF

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Page/Page column 124-125, (2010/04/03)

The present application relates to novel substituted 5-aminopyrazoles, methods of production thereof, use thereof alone or in combinations for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases.

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