121219-12-3 Usage
Uses
Used in Organic Synthesis:
4-Pentylbenzeneboronic acid is used as an intermediate in the synthesis of liquid crystals, which are essential components in the development of advanced display technologies and other applications requiring precise control over molecular orientation.
Used in Aryl Coupling Reactions:
4-Pentylbenzeneboronic acid is utilized as a reactant in aryl coupling reactions, specifically in the presence of palladium catalysts, to form new carbon-carbon bonds and create a variety of organic molecules with potential applications in pharmaceuticals, materials science, and other fields.
Used in the Suzuki Reaction:
4-Pentylbenzeneboronic acid is employed as a boronic acid component in the Suzuki reaction, a widely used cross-coupling process for the formation of carbon-carbon bonds. This reaction is particularly valuable for the synthesis of complex organic molecules and the development of new pharmaceuticals and materials.
Used in Cannabinol (C175350) Synthesis:
As a key intermediate, 4-Pentylbenzeneboronic acid is used in the synthesis of Cannabinol (C175350), a compound with potential therapeutic applications. Its involvement in this process highlights the compound's importance in the development of novel pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 121219-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,2,1 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 121219-12:
(8*1)+(7*2)+(6*1)+(5*2)+(4*1)+(3*9)+(2*1)+(1*2)=73
73 % 10 = 3
So 121219-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H17BO2/c1-2-3-4-5-10-6-8-11(9-7-10)12(13)14/h6-9,13-14H,2-5H2,1H3
121219-12-3Relevant articles and documents
Sequential one-pot access to molecular diversity through aniline aqueous borylation
Erb, William,Albini, Mathieu,Rouden, Jacques,Blanchet, Jrme
, p. 10568 - 10580 (2015/01/08)
On the basis of our recently reported aniline aqueous borylation, molecular diversity was achieved in a one-pot process by combining other reactions such as esterification, Suzuki-Miyaura coupling, hydrogenolysis, or Petasis borono-Mannich.
Design and synthesis of boronic acid inhibitors of endothelial lipase
O'Connell, Daniel P.,Leblanc, Daniel F.,Cromley, Debra,Billheimer, Jeffrey,Rader, Daniel J.,Bachovchin, William W.
, p. 1397 - 1401 (2012/03/26)
Endothelial lipase (EL) and lipoprotein lipase (LPL) are homologous lipases that act on plasma lipoproteins. EL is predominantly a phospholipase and appears to be a key regulator of plasma HDL-C. LPL is mainly a triglyceride lipase regulating (V)LDL levels. The existing biological data indicate that inhibitors selective for EL over LPL should have anti-atherogenic activity, mainly through increasing plasma HDL-C levels. We report here the synthesis of alkyl, aryl, or acyl-substituted phenylboronic acids that inhibit EL. Many of the inhibitors evaluated proved to be nearly equally potent against both EL and LPL, but several exhibited moderate to good selectivity for EL.
