1224288-95-2 Usage
General Description
5-Oxo-4,5-dihydropyrazolo[1,5-a]pyriMidine-3-carbonitrile is a chemical compound with the molecular formula C7H4N4O and a molecular weight of 156.137 g/mol. It is a heterocyclic organic compound with a pyrazole ring structure containing a carbonitrile functional group, and a ketone group. 5-Oxo-4,5-dihydropyrazolo[1,5-a]pyriMidine-3-carbonitrile is often used as a building block in the synthesis of various organic molecules. It has potential applications in the pharmaceutical and agrochemical industries, and it is also used in research and development for its unique structural properties and reactivity. Additionally, it may have biological activity and therapeutic potential, making it a target for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1224288-95-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,4,2,8 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1224288-95:
(9*1)+(8*2)+(7*2)+(6*4)+(5*2)+(4*8)+(3*8)+(2*9)+(1*5)=152
152 % 10 = 2
So 1224288-95-2 is a valid CAS Registry Number.
1224288-95-2Relevant articles and documents
COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO NTRK
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Page/Page column 27; 28, (2017/06/12)
This invention relates to inhibitors of NTRK comprising a pyrazolo[1,5-4]pyrimidine-3-carbonitrile structure. They are active against wild-type NTRK and its resistant mutants.
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS
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Page/Page column 93, (2011/02/24)
Compounds of Formula (I) and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
