122567-92-4Relevant articles and documents
Dihydropyrimidines: Novel calcium antagonists with potent and long-lasting vasodilative and antihypertensive activity
Cho,Ueda,Shima,Mizuno,Hayashimatsu,Ohnaka,Takeuchi,Hamaguchi,Aisaka,Hidaka,Kawai,Takeda,Ishihara,Funahashi,Satoh,Morita,Noguchi
, p. 2399 - 2406 (2007/10/02)
The novel calcium antagonists 3-N-substituted-3,4-dihydropyrimidines 1 and 9 and 3-N-substituted-dihydropyrimidin-2(1H)-ones 8 were regioselectively synthesized in good yields. Compounds 1 [especially 1s [R1 = (CH2)2N(benz