1227270-38-3 Usage
Uses
Used in Pharmaceutical Industry:
Methyl 5-fluoro-1H-indazole-6-carboxylate is used as a building block for the synthesis of various pharmaceutical drugs due to its unique structure and properties. It serves as a key intermediate in the development of potential drug candidates, contributing to the creation of novel therapeutic agents with improved efficacy and safety profiles.
Used in Chemical Research:
In the field of chemical research, Methyl 5-fluoro-1H-indazole-6-carboxylate is utilized as a valuable compound for studying the properties and reactions of indazole derivatives. Its unique structure allows researchers to explore new chemical pathways and mechanisms, potentially leading to the discovery of innovative applications and advancements in the field.
Used in Material Science:
Methyl 5-fluoro-1H-indazole-6-carboxylate may also find potential applications in material science, where its unique properties can be harnessed to develop new materials with specific characteristics. Its role in this field could include the creation of advanced materials for various industries, such as electronics, coatings, or sensors, where its properties can be tailored to meet specific requirements.
Check Digit Verification of cas no
The CAS Registry Mumber 1227270-38-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,2,7 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1227270-38:
(9*1)+(8*2)+(7*2)+(6*7)+(5*2)+(4*7)+(3*0)+(2*3)+(1*8)=133
133 % 10 = 3
So 1227270-38-3 is a valid CAS Registry Number.
1227270-38-3Relevant articles and documents
Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain
Luo, Guanglin,Chen, Ling,Easton, Amy,Newton, Amy,Bourin, Clotilde,Shields, Eric,Mosure, Kathy,Soars, Matthew G.,Knox, Ronald J.,Matchett, Michele,Pieschl, Rick L.,Post-Munson, Debra J.,Wang, Shuya,Herrington, James,Graef, John,Newberry, Kimberly,Sivarao, Digavalli V.,Senapati, Arun,Bristow, Linda J.,Meanwell, Nicholas A.,Thompson, Lorin A.,Dzierba, Carolyn
, p. 831 - 856 (2019/01/21)
3-Aryl-indole and 3-aryl-indazole derivatives were identified as potent and selective Nav1.7 inhibitors. Compound 29 was shown to be efficacious in the mouse formalin assay and also reduced complete Freund's adjuvant (CFA)-induced thermal hyper
GPR40 RECEPTOR AGONIST, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT
-
, (2014/05/24)
The present invention relates to a novel compound having GPR40 receptor agonist activity that promotes insulin secretion and inhibits blood sugar rise after glucose loading, and is thereby useful for the treatment of diabetes and complications thereof, the preparation method thereof and pharmaceutical composition containing them as an active ingredient.
