123089-12-3

Basic information

• Product Name: 5-bromo-2-(1-methyl-2-propenyloxy)pyrimidine
• Synonyms: 5-bromo-2-(1-methyl-2-propenyloxy)pyrimidine
• CAS NO: 123089-12-3
• Molecular Formula: C8H9BrN2O
• Molecular Weight: 229
• Mol File: 123089-12-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-bromo-2-(1-methyl-2-propenyloxy)pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-(1-methyl-2-propenyloxy)pyrimidine(123089-12-3)
• EPA Substance Registry System: 5-bromo-2-(1-methyl-2-propenyloxy)pyrimidine(123089-12-3)

Safety Data

• Hazardous Substances Data: 123089-12-3(Hazardous Substances Data)

Upstream product

• 598-32-3 2-hydroxy-3-butene 
• 32779-36-5 5-Bromo-2-chloropyrimidine 

Relevant articles and documents

Palladium Catalysis in Allylic Alkylations and Rearrangements in Pyrimidines

The regiochemistry of the alkylation of 2-pyrimidinones with ?-allylpalladium complexes from allylic acetates and Pd(0) depends on the substitution pattern in the allylic system.In Pd(II)-catalysed rearrangements of 2-propenyloxypyrimidines the preference for a 1,3-rearrangement or the Claisen 3,3-rearrangement is influenced by the substitution pattern in the allylic system.Pd(0) forms ?-allylpalladium complexes with 2-propenyloxypyrimidines which give rise to rearrangement products.The product ratios in the Pd(II) and Pd(0) rearrangements in unsymmetrically substituted allylic systems are different.The rearrangement reactions, especially the Pd(II) rearrangement, give access to products which are difficult to prepare by direct alkylation.