123191-00-4Relevant articles and documents
The synthesis of 4-substituted indoles via arenetricarbonylchromium(0) complexes
Beswick,Greenwood,Mowlem,Nechvatal,Widdowson
, p. 7325 - 7334 (1988)
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NOVEL PYRIDIN-2(1H)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF PAIN
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Page/Page column 15; 22-23, (2021/04/10)
The present invention concerns novel pyridin-2(1H)one derivatives, their process of preparation and their use in therapeutics, in particular as agents for treating and/or preventing pain.
Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids
Das, Amrita,Watanabe, Kenji,Morimoto, Hiroyuki,Ohshima, Takashi
supporting information, p. 5794 - 5797 (2017/11/10)
Boronic acid was used to accelerate a three-component reaction of indoles, thiols, and glyoxylic acids for the synthesis of α-sulfanyl-substituted indole-3-acetic acids. Boronic acid catalysis to activate the α-hydroxy group in α-hydroxycarboxylic acid in
4-Substituted Pyrrolo[2,3-d]pyrimidine Compound and Use Thereof
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Paragraph 0045; 0046; 0071; 0072; 0095; 0096, (2016/12/07)
The invention relates to a 4-substituted pyrrolo[2,3-d]pyrimidine compound and the use thereof in preparing medications for treating JAK-targeted diseases such as rheumatoid, immune system diseases, and tumor. The 4-substituted pyrrolo[2,3-d]pyrimidine compound of the invention is as shown in chemical formula I. The activity experimental results of the invention show that the new compound has obvious effect and activity in inhibition of Janus kinases, JAK-STAT, cell proliferation of human lymphocytoma, and rheumatoid arthritis.