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123191-00-4

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123191-00-4 Usage

General Description

1-(triisopropylsilyl)indole is a chemical compound that consists of an indole ring with a triisopropylsilyl group attached to the nitrogen atom. 1-(TRIISOPROPYLSILYL)INDOLE is often used as a protecting group in organic synthesis, allowing for the selective reaction of other functional groups while keeping the indole ring intact. The triisopropylsilyl group can be easily removed under mild conditions, making it a versatile tool in the synthesis of complex organic molecules. Additionally, 1-(triisopropylsilyl)indole has been studied for its potential biological activities, including its ability to inhibit certain enzymes and receptors in the central nervous system. Overall, this compound has applications in both organic synthesis and medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 123191-00-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,1,9 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 123191-00:
(8*1)+(7*2)+(6*3)+(5*1)+(4*9)+(3*1)+(2*0)+(1*0)=84
84 % 10 = 4
So 123191-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H27NSi/c1-13(2)19(14(3)4,15(5)6)18-12-11-16-9-7-8-10-17(16)18/h7-15H,1-6H3

123191-00-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(Triisopropylsilyl)indole

1.2 Other means of identification

Product number -
Other names indol-1-yl-tri(propan-2-yl)silane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123191-00-4 SDS

123191-00-4Relevant articles and documents

The synthesis of 4-substituted indoles via arenetricarbonylchromium(0) complexes

Beswick,Greenwood,Mowlem,Nechvatal,Widdowson

, p. 7325 - 7334 (1988)

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NOVEL PYRIDIN-2(1H)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF PAIN

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Page/Page column 15; 22-23, (2021/04/10)

The present invention concerns novel pyridin-2(1H)one derivatives, their process of preparation and their use in therapeutics, in particular as agents for treating and/or preventing pain.

Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids

Das, Amrita,Watanabe, Kenji,Morimoto, Hiroyuki,Ohshima, Takashi

supporting information, p. 5794 - 5797 (2017/11/10)

Boronic acid was used to accelerate a three-component reaction of indoles, thiols, and glyoxylic acids for the synthesis of α-sulfanyl-substituted indole-3-acetic acids. Boronic acid catalysis to activate the α-hydroxy group in α-hydroxycarboxylic acid in

4-Substituted Pyrrolo[2,3-d]pyrimidine Compound and Use Thereof

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Paragraph 0045; 0046; 0071; 0072; 0095; 0096, (2016/12/07)

The invention relates to a 4-substituted pyrrolo[2,3-d]pyrimidine compound and the use thereof in preparing medications for treating JAK-targeted diseases such as rheumatoid, immune system diseases, and tumor. The 4-substituted pyrrolo[2,3-d]pyrimidine compound of the invention is as shown in chemical formula I. The activity experimental results of the invention show that the new compound has obvious effect and activity in inhibition of Janus kinases, JAK-STAT, cell proliferation of human lymphocytoma, and rheumatoid arthritis.

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