123296-57-1Relevant articles and documents
Synthesis and antirheumatic activity of novel tetrahydroquinoline-8-carboxylic acid derivatives
Kohno, Yasushi,Awano, Katsuya,Miyashita, Mitsutomo,Fujimori, Shizuyoshi,Kuriyama, Kazuhiko,Sakoe, Yasuhiko,Kudoh, Shinji,Saito, Koji,Kojima, Eisuke
, p. 1515 - 1518 (2007/10/03)
A study of the modification of N-alkylanthranilic acids to develop novel DMARDs is detailed. 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid derivatives were found to exhibit a therapeutic effect on adjuvant arthritis and a suppressive effect on bone destruction.
Cyclic anthranilic acid derivatives and process for their preparation
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, (2008/06/13)
An antirheumatoid pharmaceutical composition containing a cyclic anthranilic acid derivative of the following formula, STR1 wherein R1, R2 and R3 each independently indicate a hydrogen atom, lower alkyl group having 1 to 3