1233713-11-5

Basic information

• Product Name: 1-(3-amino-4-isopropylphenyl)-2,2,2-trifluoroethanone
• Synonyms: 1-(3-amino-4-isopropylphenyl)-2,2,2-trifluoroethanone
• CAS NO: 1233713-11-5
• Molecular Weight: 231.218
• Mol File: 1233713-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-amino-4-isopropylphenyl)-2,2,2-trifluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-amino-4-isopropylphenyl)-2,2,2-trifluoroethanone(1233713-11-5)
• EPA Substance Registry System: 1-(3-amino-4-isopropylphenyl)-2,2,2-trifluoroethanone(1233713-11-5)

Safety Data

• Hazardous Substances Data: 1233713-11-5(Hazardous Substances Data)

Upstream product

• 1233713-10-4 2,2,2-trifluoro-1-(4-isopropyl-3-nitrophenyl)ethanone 

Downstream Products

• 1233713-12-6 2,2,2-trifluoro-1-(3-hydroxy-4-isopropylphenyl)ethanone 

Relevant articles and documents

M -Azipropofol (AziP m) a photoactive analogue of the intravenous general anesthetic propofol

Propofol is the most commonly used sedative-hypnotic drug for noxious procedures, yet the molecular targets underlying either its beneficial or toxic effects remain uncertain. In order to determine targets and thereby mechanisms of propofol, we have synthesized a photoactivateable analogue by substituting an alkyldiazirinyl moiety for one of the isopropyl arms but in the meta position. m-Azipropofol retains the physical, biochemical, GABAA receptor modulatory, and in vivo activity of propofol and photoadducts to amino acid residues in known propofol binding sites in natural proteins. Using either mass spectrometry or radiolabeling, this reagent may be used to reveal sites and targets that underlie the mechanism of both the desirable and undesirable actions of this important clinical compound.