1238210-10-0 Usage
Uses
Used in Pharmaceutical Industry:
Emtricitabine Carboxylic Acid is used as an impurity in the production of the antiviral agent Emtricitabine (E525035) for the treatment of HIV-1 infection. Its presence in the final product should be minimized to ensure the safety and efficacy of the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 1238210-10-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,8,2,1 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1238210-10:
(9*1)+(8*2)+(7*3)+(6*8)+(5*2)+(4*1)+(3*0)+(2*1)+(1*0)=110
110 % 10 = 0
So 1238210-10-0 is a valid CAS Registry Number.
1238210-10-0Relevant articles and documents
Stereoselective synthesis of nucleoside analogues using bicyclic intermediate
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, (2008/06/13)
The present invention relates to a process for producing predominantly pure cis nucleoside analogues of formula (I), wherein X is S, or O; Y is S, CH2, O or CH(R); wherein R is azido or halogen; and R2 is a purine or pyrimidine base; via the coupling of a silylated purine or pyrimidine base in the presence of an appropriate Lewis acid with a bicyclic intermediate of formula (III) wherein Z is S or O; followed by conversion of the resulting intermediate of formula (II) to an alkyl ester and reduction to yield a compound of formula (I). STR1
