124436-59-5

Basic information

• Product Name: pirodavir
• Synonyms: pirodavir;Ethyl p-[2-[1-(6-Methylpyridazin-3-yl)piperidin-4-yl]-ethoxy]benzoate;Benzoic acid, 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, ethyl ester;ethyl p-(2-(1-(6-Methyl-3-pyridazinyl)-4-piperidyl)ethoxy) benzoate;R 77975;R77975;R-77975;Ethyl 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoate
• CAS NO: 124436-59-5
• Molecular Formula: C21H27N3O3
• Molecular Weight: 369.462
• Product Categories: Inhibitors
• Mol File: 124436-59-5.mol

Chemical Properties

• Melting Point: 124-125℃
• Boiling Point: 572°Cat760mmHg
• Flash Point: 299.8°C
• Appearance: /
• Density: 1.137g/cm³
• Vapor Pressure: 4.28E-13mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: pirodavir(CAS DataBase Reference)
• NIST Chemistry Reference: pirodavir(124436-59-5)
• EPA Substance Registry System: pirodavir(124436-59-5)

Safety Data

• Hazardous Substances Data: 124436-59-5(Hazardous Substances Data)

Usage

Uses

Used in Antiviral Applications:
Pirodavir is used as an antiviral agent for modulating lipophilicity in human rhinovirus capsid binders, which aids in the identification and development of potential antiviral agents. Its broad-spectrum activity against different picornaviruses, including rhinoviruses, coxsackievirus, poliovirus, and echovirus, makes it a promising candidate for treating various viral infections.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, pirodavir is used as a compound for identifying potential antiviral agents. Its effectiveness against a wide range of picornaviruses makes it a valuable tool in the development of new antiviral drugs and therapies.

InChI:InChI=1/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 124438-52-4 3-methyl-6-[4-(2-chloroethyl)-1-piperidynyl]pyridazine 

Relevant articles and documents

An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus

A series of capsid-binding compounds was screened against human rhinovirus (HRV) using a CPE based assay. The ethyl oxime ether 14 was found to have outstanding anti-HRV activity (median IC50 4.75 ng/mL), and unlike the equivalent ethyl ester c

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