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7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one, commonly referred to as BMO, is a white solid compound with the molecular formula C10H10BrNO2. It is a member of the oxazine family, characterized by the presence of a bromo substituent at the 7-position and two methyl groups at the 4-position on the benzene ring. 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one is recognized for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as for its possible biological activities such as antibacterial and anticancer properties. The full extent of its applications and effects is an ongoing area of research, and safety precautions are essential when handling this chemical.

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  • 1245643-21-3 Structure
  • Basic information

    1. Product Name: 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
    2. Synonyms: 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one;7-Bromo-1,4-dihydro-4,4-dimethyl-2H-3,1-benzoxazin-2-one;7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)
    3. CAS NO:1245643-21-3
    4. Molecular Formula: C10H10BrNO2
    5. Molecular Weight: 256
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1245643-21-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 258℃
    3. Flash Point: 110℃
    4. Appearance: /
    5. Density: 1.468
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one(1245643-21-3)
    11. EPA Substance Registry System: 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one(1245643-21-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1245643-21-3(Hazardous Substances Data)

1245643-21-3 Usage

Uses

Used in Pharmaceutical Synthesis:
7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one serves as a precursor in the production of pesticides and herbicides. Its chemical properties allow for the creation of effective compounds designed to protect crops from pests and unwanted plant growth.
Used in Antibacterial Applications:
7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one is studied for its potential antibacterial properties. It may be used as an active ingredient in antimicrobial formulations to combat bacterial infections, contributing to the development of new antibiotics in the face of increasing antibiotic resistance.
Used in Anticancer Research:
7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one is also being investigated for its possible anticancer properties. Researchers are exploring its potential to target and inhibit the growth of cancer cells, which could lead to the development of novel cancer therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 1245643-21-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,6,4 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1245643-21:
(9*1)+(8*2)+(7*4)+(6*5)+(5*6)+(4*4)+(3*3)+(2*2)+(1*1)=143
143 % 10 = 3
So 1245643-21-3 is a valid CAS Registry Number.

1245643-21-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-bromo-4,4-dimethyl-1H-3,1-benzoxazin-2-one

1.2 Other means of identification

Product number -
Other names 7-bromo-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1245643-21-3 SDS

1245643-21-3Downstream Products

1245643-21-3Relevant articles and documents

SYK INHIBITORS

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, (2016/10/07)

The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)

8 - SUBSTITUTED 2 -AMINO - [1,2,4] TRIAZOLO [1, 5 -A] PYRAZINES AS SYK TRYROSINE KINASE INHIBITORS AND GCN2 SERIN KINASE INHIBITORS

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Page/Page column 173, (2013/09/12)

Compounds of the formula I in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of cancer, rheumatoid arthritis and / or systemic lupus

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