124571-67-1Relevant articles and documents
Increasing Scope of Clickable Fluorophores: Electrophilic Substitution of Ylidenemalononitriles
De Souza, Juliana M.,Abdiaj, Irini,Chen, Jiaqi,Hanson, Kenneth,De Oliveira, Kleber T.,McQuade, D. Tyler
, p. 11822 - 11834 (2020)
Recently, we demonstrated that ylidenemalononitriles (YMs) react with amines to form cyclic amidines and that the starting linear YMs are nonemissive in solution and the cyclic amidines are fluorescent. These turn-on systems were of interest to us because of their potential as biosensors and synthons for accessing functionalized pyridines. While our original method was promising, several limitations persisted, including access to more functionalized and polar-solvent-soluble structures as well as increased control over the rate of cyclization. Herein, we report a new approach that allows the electrophilic substitution of YMs. These substituted YMs exhibit faster turn-on rates, color tunability, access to polar-solvent-soluble species, and increased control over cyclization rate. This allowed us to significantly expand the fluorophore's chemical space.
Gas-phase pyrolysis of 2-heteroaromatic-1-dimethylaminoethylenes: kinetic and mechanistic study
Elnagdi, Mohamed H.,Al-Awadi, Nouria A.,Kumar, Agith,Khalik, Mervat Abdul
, p. 47 - 51 (2007/10/03)
Gas-phase pyrolysis reactions of 4(2′-dimethylaminoethenyl)-2-oxo-2H- benzo[b]pyran-3-carbonitrile (1), 4(2′-dimethylaminoethenyl)-2-oxo-2H- naphtho[1,2-b]pyran-3-carbonitrile (2), 1,6-dihydro-4-(2′-dimethylaminoethenyl)-6- oxo-1-phenylpyridazine-3,5-dica
Reaction between 2-phenyl-1,1-dicyanoallyl anion and N-methyl-2,2-dimethylpropionitrilium and N1,N2,N 2-trimethyl-2,2-dimethylpropionylamidinium trifluoromethanesulfonates
Kolsaker, Per,Karlsen, Hege,Romming, Christian
, p. 623 - 632 (2007/10/03)
The reaction of 2-phenyl-1,1-dicyanoallyl anion with N-methyl-2,2-dimethylpropionitrilium ion (2) in acetonitrile solution resulted in formation of [3-(N-methylamino)-4,4-dimethyl-1-phenyl-2-pentenylidene]propanedinitrile (6), which at elevated temperatur