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Cedrelone, a natural chemical compound derived from the heartwood of Cedrela or mahogany trees, is renowned for its potent antimicrobial and insecticidal properties. This bioactive substance has garnered attention for its potential applications in traditional medicine, insect repellents, and beyond, due to its demonstrated anti-cancer and anti-inflammatory properties in laboratory settings. Cedrelone's distinctive chemical structure and its wide-ranging biological activities position it as a promising candidate for future research and development in pharmaceutical and agricultural sectors.

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  • 1254-85-9 Structure
  • Basic information

    1. Product Name: cedrelone
    2. Synonyms: cedrelone;(13α,17α)-14β,15β:21,23-Diepoxy-6-hydroxy-4,4,8-trimethyl-24-norchola-1,5,20,22-tetrene-3,7-dione
    3. CAS NO:1254-85-9
    4. Molecular Formula: C26H30O5
    5. Molecular Weight: 422.5134
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1254-85-9.mol
  • Chemical Properties

    1. Melting Point: 204 °C
    2. Boiling Point: 584.2°Cat760mmHg
    3. Flash Point: 307.1°C
    4. Appearance: /
    5. Density: 1.3g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.618
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 8.59±0.70(Predicted)
    11. CAS DataBase Reference: cedrelone(CAS DataBase Reference)
    12. NIST Chemistry Reference: cedrelone(1254-85-9)
    13. EPA Substance Registry System: cedrelone(1254-85-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1254-85-9(Hazardous Substances Data)

1254-85-9 Usage

Uses

Used in Traditional Medicine:
Cedrelone is utilized as a therapeutic agent for its antimicrobial and insecticidal properties, serving as a key component in traditional remedies to combat infections and pests.
Used in Insect Repellents:
In the industry of insect repellents, cedrelone is employed as an active ingredient for its insecticidal effects, providing protection against various insects and enhancing the efficacy of repellent products.
Used in Pharmaceutical Research:
Cedrelone is used as a subject of research for its potential anti-cancer properties, with laboratory experiments indicating its ability to target and inhibit the growth of cancer cells.
Used in Anti-Inflammatory Applications:
In the realm of anti-inflammatory agents, cedrelone is studied for its capacity to reduce inflammation, offering a natural alternative for the treatment of conditions characterized by excessive inflammation.
Used in Agricultural Industries:
Cedrelone is applied as a biopesticide in agriculture, leveraging its insecticidal properties to protect crops from harmful insects, thereby increasing yield and reducing the reliance on chemical pesticides.
Each of these applications underscores the versatility and potential of cedrelone, highlighting its value across different industries and spurring ongoing research to unlock its full potential.

Check Digit Verification of cas no

The CAS Registry Mumber 1254-85-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,5 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1254-85:
(6*1)+(5*2)+(4*5)+(3*4)+(2*8)+(1*5)=69
69 % 10 = 9
So 1254-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C26H30O5/c1-22(2)17(27)7-9-23(3)16-6-10-24(4)15(14-8-11-30-13-14)12-18-26(24,31-18)25(16,5)21(29)19(28)20(22)23/h7-9,11,13,15-16,18,28H,6,10,12H2,1-5H3/t15-,16+,18+,23+,24-,25-,26+/m0/s1

1254-85-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name AC1MJ135

1.2 Other means of identification

Product number -
Other names 14,15,21,23-Diepoxy-6-hydroxy-4,4,8-trimethyl-24-nor-chola-1,5,20,22-tetraen-3,7-dion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1254-85-9 SDS

1254-85-9Downstream Products

1254-85-9Relevant articles and documents

Ethylenediamine: An effective reagent for deacetylation of natural products

Mohankumar, Ramasamy,Ilango, Kaliappan,Santhanakrishnan, Vichangal Pridiuldi,Radhakrishnan, Viswanathan,Narasimhan, Srinivasan

experimental part, p. 851 - 858 (2010/12/25)

The use of ethylenediamine in methanol is described for the selective cleavage of the acetate group in nimbin (1) to 6-deacetyl nimbin (1a) under microwave irradiation. This method enables to deacetylate without affecting other functional groups such as ,α,β-unsaturated ketone, ester, ether, etc. in certain tetranortriterpenoids and other acetate-containing natural compounds.

New Limonoids from the Roots of Melia azedarach Linn.

Srivastava, Santosh K.,Gupta, Hari O.

, p. 166 - 170 (2007/10/02)

Chemical and spectral evidences are presented for the structure of salannin, a new limonoid, 6-acetoxy-7α-hydroxy-3-oxo-14β,15β-epoxymeliac-1,5-diene and a new limonoid glycoside, 6-acetoxy-3β-hydroxy-7-oxo-14β,15β-epoxymeliac-1,5-diene-3-O-β-D-glucuronopyranoside isolated from the roots of Melia azedarach Linn.

A Correlation of Azadirone with Cedrelone

Natarajan, S.,Chandrasekharan, S.,Govindachari, T. R.,Pai, B. R.

, p. 1061 - 1064 (2007/10/02)

Azadirone (I) has been hydrolysed and the resulting alcohol (VIII) oxidised to a 7-keto compound (IX) which on Barton oxidation yields 1,2-epoxycedrelone (XIII), cedrelone (VII) and two carboxylic acids (XIV) and (XV) derived by a benzilic acid rearrangement.Thus the neem limonoids have been correlated with cedrelone.

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