1262660-98-9

Basic information

• Product Name: N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninyl-proline N'-methylamide
• Synonyms: N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninyl-proline N'-methylamide
• CAS NO: 1262660-98-9
• Molecular Weight: 544.653
• Mol File: 1262660-98-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninyl-proline N'-methylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninyl-proline N'-methylamide(1262660-98-9)
• EPA Substance Registry System: N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninyl-proline N'-methylamide(1262660-98-9)

Safety Data

• Hazardous Substances Data: 1262660-98-9(Hazardous Substances Data)

Upstream product

• 1262660-95-6 C₁₈H₂₄N₂O₅S 
• 1262660-94-5 C₂₁H₂₈N₂O₅S 
• 1262660-93-4 C₁₅H₂₄N₂O₃ 
• 1262660-92-3 C₁₅H₂₅NO₅ 
• 940312-40-3 C₁₆H₂₇NO₄ 
• 1262660-97-8 (2S)-N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alanine 
• 33208-98-9 pyrrolidine-2-carboxylic acid methylamide hydrochloride 
• 1262660-96-7 (2S)-N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alaninol 

Relevant articles and documents

Synthesis and peptide coupling of protected 2-pyrrolylalanine

2-Pyrrolylalanine has been synthesized in two protected forms and applied in the solution-phase synthesis of a dipeptide. (2S)-N-(Boc)-N′- (phenylsulfonyl)- and (2S)-N,N′-bis-(phenylsulfonyl)-3-(2-pyrrolyl) alanines (7 and 9) were obtained, respectively, in 14% and 13% overall yields and six and seven steps from oxazolidine β-methyl ester 1, which was derived from l-aspartic acid. Homoallylic ketone 2 was obtained from a copper-catalyzed cascade addition of vinylmagnesium bromide to 1 and converted into pyrrolylalanines 7 and 9 by a sequence featuring subsequent olefin oxidation and Paal-Knorr condensation. Protected pyrrolylalanine 9 was then introduced into a dipeptide. Crown Copyright