1264015-76-0 Usage
Explanation
This compound is characterized by its intricate structure that includes a long chain of ethoxy (–OCH2CH3) groups and aminoethoxy groups, indicating a molecule with multiple repeating units and a high degree of functionalization.
2. Presence of Tosylate Group
Explanation: The tosylate group (p-toluenesulfonate, –OTs) is a well-known leaving group in organic chemistry, implying the compound's potential utility in nucleophilic substitution reactions where the tosylate group is displaced by a nucleophile.
3. Tert-butoxycarbonyl (Boc) Group
Explanation: The Boc group is a common amine-protecting group used in organic synthesis. Its presence suggests the compound can serve as a protected amine precursor, allowing for selective reactions at other sites of the molecule without affecting the amine functionality.
4. Applications in Organic Synthesis
Explanation: Given its structural features—particularly the protective Boc group and the tosylate leaving group—the compound likely finds use in the synthesis of other complex molecules, serving as a building block or reagent in organic synthesis.
5. Potential for Nucleophilic Substitution Reactions
Explanation: The tosylate group's inclusion points towards the compound's utility in nucleophilic substitution reactions, which are fundamental in creating new carbon-nitrogen, carbon-oxygen, or carbon-carbon bonds in organic synthesis.
6. Usefulness as a Reagent or Precursor
Explanation: Due to its complex structure and functional groups, the compound can be used as a reagent or precursor for producing other compounds, especially in synthesizing molecules that require protected amine functionalities or specific ethoxy chain lengths.
7. Unique Properties for Chemical Processes
Explanation: The specific arrangement of ethoxy and aminoethoxy groups combined with the presence of a Boc protecting group and a tosylate leaving group endows the molecule with unique properties, making it valuable for various chemical processes, including those requiring high specificity and selectivity.
8. Versatility in Synthesis
Explanation: The structural features of this compound suggest its versatility in synthesis, enabling its use in diverse chemical reactions and as a component in the synthesis of polymers, pharmaceuticals, or materials science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1264015-76-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,4,0,1 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1264015-76:
(9*1)+(8*2)+(7*6)+(6*4)+(5*0)+(4*1)+(3*5)+(2*7)+(1*6)=130
130 % 10 = 0
So 1264015-76-0 is a valid CAS Registry Number.
1264015-76-0Relevant articles and documents
THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE
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, (2022/02/15)
The present application is directed to a therapeutic composition, comprising two precursor compounds (monomers) that are suitable for assembly via two or more reversible covalent bonds. The monomers are polyfunctionalized molecules comprising a bioorthogo
Solid-Phase-Based Synthesis of Ureidopyrimidinone-Peptide Conjugates for Supramolecular Biomaterials
De Feijter, Isja,Goor, Olga J. G. M.,Hendrikse, Simone I. S.,Comellas-Aragonès, Marta,S?ntjens, Serge H. M.,Zaccaria, Sabrina,Fransen, Peter P. K. H.,Peeters, Joris W.,Milroy, Lech-Gustav,Dankers, Patricia Y. W.
, p. 2707 - 2713 (2015/11/27)
Supramolecular polymers have shown to be powerful scaffolds for tissue engineering applications. Supramolecular biomaterials functionalized with ureidopyrimidinone (UPy) moieties, which dimerize via quadruple hydrogen-bond formation, are eminently suitable for this purpose. The conjugation of the UPy moiety to biologically active peptides ensures adequate integration into the supramolecular UPy polymer matrix. The structural complexity of UPy-peptide conjugates makes their synthesis challenging and until recently low yielding, thus restricted the access to structurally diverse derivatives. Here we report optimization studies of a convergent solid-phase based synthesis of UPy-modified peptides. The peptide moiety is synthesized using standard Fmoc solid-phase synthesis and the UPy fragment is introduced on the solid-phase simplifying the synthesis and purification of the final UPy-peptide conjugate. The convergent nature of the synthesis reduces the number of synthetic steps in the longest linear sequence compared to other synthetic approaches. We demonstrate the utility of the optimized route by synthesizing a diverse range of biologically active UPy-peptide bioconjugates in multimilligram scale for diverse biomaterial applications. 1 Introduction 2 Divergent Synthesis 3 Convergent Synthesis 4 UPy-Amine Strategy 5 UPy-Carboxylic Acid Strategy 6 Conclusion.
