126422-58-0

Basic information

• Product Name: Bis-Propargyl-PEG4
• Synonyms: Bis-Propargyl-PEG4;Alkyne-PEG4-Alkyne;4,7,10,13-Tetraoxahexadeca-1,15-diyne
• CAS NO: 126422-58-0
• Molecular Formula: C₁₂H₁₈O₄
• Molecular Weight: 226.26892
• Mol File: 126422-58-0.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bis-Propargyl-PEG4(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-Propargyl-PEG4(126422-58-0)
• EPA Substance Registry System: Bis-Propargyl-PEG4(126422-58-0)

Safety Data

• Hazardous Substances Data: 126422-58-0(Hazardous Substances Data)

Usage

Description

Bis-propargyl-PEG4 enables Click Chemistry reactions with azide compounds via copper catalyzed azide-alkyne Click Chemistry. The PEG units enhance the solubility of the molecule in aqueous media.

Upstream product

• 106-96-7 propargyl bromide 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 31255-10-4 1,2-bis-(2-bromo-ethoxy)-ethane 
• 107-19-7 propargyl alcohol 

Downstream Products

• 1014613-84-3 C₃₂H₄₄N₈O₁₄P₂ 

Relevant articles and documents

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO2

By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO2 into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of primary propargylic alcohols. The silver-DavePhos catalyst is further applied for the bis-carboxylative cyclization of primary propargyl derivatives, thereby providing an effective route to a series of previously inaccessible and industrially relevant α-alkylidene cyclic carbonates.

Strapped calix[4]pyrrole as a lithium salts selective receptor through separated ion-pair binding

A triazole-bearing strapped calix[4]pyrrole (1) was synthesized as a lithium salt selective ion pair receptor. 1H NMR spectral studies and X-ray crystallography showed that the capture of LiCl by 1 occurs via separated ion pair binding. Furthermore, lithium salts extracted by 1 could be solidified in the form of Li2CO3 through CO2 or K2CO3 treatment.

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO2

By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO2 into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of primary propargylic alcohols. The silver-DavePhos catalyst is further applied for the bis-carboxylative cyclization of primary propargyl derivatives, thereby providing an effective route to a series of previously inaccessible and industrially relevant α-alkylidene cyclic carbonates.