126443-17-2Relevant articles and documents
Synthesis of some new pyrazolines and isoxazoles carrying 4-methylthiophenyl moiety as potential analgesic and antiinflammatory agents
Karabasanagouda,Adhikari, Airody Vasudeva,Girisha
experimental part, p. 430 - 437 (2009/12/26)
A series of new pyrazolines 3a-m and isoxazoies 4a-k have been synthesized from 4-acetylthioanisole, 1 with aryl aldehydes through α, β-unsaturated ketones. The structures of the newly synthesized compounds have been confirmed on the basis of elemental analysis and spectral studies. The newly synthesized title compounds have been tested for their analgesic and antiinflammatory activity. Some of the compounds exhibited encouraging results.
'On water' synthesis of 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines catalysed by sodium dodecyl sulfate (SDS)
Sharma, Gaurav,Kumar, Raj,Chakraborti, Asit K.
, p. 4269 - 4271 (2008/09/21)
An efficient synthesis of 1,3-diaryl-2,3-dihydro-1,5-benzothiazepines has been developed by the reaction of various 1,3-diaryl-2-propenones with 2-aminothiophenol in water under neutral conditions catalysed by SDS. Excellent chemoselectivity was observed for substrates possessing halogen atoms or nitro/alkoxy/thioalkyl groups which did not undergo competitive aromatic nucleophilic substitution of the halogen atoms or the nitro group, reduction of the nitro or the α,β-unsaturated carbonyl group, or dealkylation of the alkoxy/thioalkoxy groups.
