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AKOS B018338, with the molecular formula C10H13NO2S, is a crystalline solid chemical compound. It serves as a precursor in the synthesis of pharmaceutical compounds and organic chemical reactions. Known for its inhibitory effect on the enzyme thioredoxin reductase, which is involved in cellular redox regulation, AKOS B018338 is also utilized as a building block in the production of dyes and pigments. Its potential applications extend to the development of new drugs and organic chemistry research.

127378-26-1

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127378-26-1 Usage

Uses

Used in Pharmaceutical Synthesis:
AKOS B018338 is used as a precursor in the synthesis of pharmaceutical compounds for its ability to contribute to the development of new drugs.
Used in Organic Chemical Reactions:
AKOS B018338 is used as a building block in organic chemical reactions, facilitating the creation of various chemical products.
Used in Dye and Pigment Production:
AKOS B018338 is used as a building block in the production of dyes and pigments, contributing to the coloration and properties of these substances.
Used in Enzyme Inhibition:
AKOS B018338 is used as an inhibitor of the enzyme thioredoxin reductase, playing a role in cellular redox regulation and potentially contributing to the development of treatments for diseases associated with redox imbalances.
Used in Organic Chemistry Research:
AKOS B018338 is utilized in the field of organic chemistry research to explore its properties, reactions, and potential applications in creating new chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 127378-26-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,3,7 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127378-26:
(8*1)+(7*2)+(6*7)+(5*3)+(4*7)+(3*8)+(2*2)+(1*6)=141
141 % 10 = 1
So 127378-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NOS2/c1-7-3-2-4-8(5-7)6-9-10(13)12-11(14)15-9/h2-6H,1H3,(H,12,13,14)/b9-6+

127378-26-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (5E)-2-Mercapto-5-(3-methylbenzylidene)-1,3-thiazol-4(5H)-one

1.2 Other means of identification

Product number -
Other names (5E)-5-[(3-methylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127378-26-1 SDS

127378-26-1Downstream Products

127378-26-1Relevant articles and documents

Discovery of low-molecular-weight ligands for the AF6 PDZ domain

Joshi, Mangesh,Vargas, Carolyn,Boisguerin, Prisca,Diehl, Annette,Krause, Gerd,Schmieder, Peter,Moelling, Karin,Hagen, Volker,Schade, Markus,Oschkinat, Hartmut

, p. 3790 - 3795 (2006)

In the groove: The "drugability" of protein-protein interaction domains is still a matter of debate. The 3D structure of a complex of a small organic ligand and the AF6 PDZ domain revealed the creation of a binding pocket by the ligand (see picture). The

CHARGE CONTROLLING AGENT AND TONER USING SAME

-

Page/Page column 24, (2013/02/27)

The present invention provides a charge control agent containing, as an active substance(s), one or two or more rhodanine compounds represented by the following formula (1). where R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, a linea

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2

Russell, Angela J.,Westwood, Isaac M.,Crawford, Matthew H.J.,Robinson, James,Kawamura, Akane,Redfield, Christina,Laurieri, Nicola,Lowe, Edward D.,Davies, Stephen G.,Sim, Edith

experimental part, p. 905 - 918 (2009/09/25)

The identification, synthesis and evaluation of a series of rhodanine and thiazolidin-2,4-dione derivatives as selective inhibitors of human arylamine N-acetyltransferase 1 and mouse arylamine N-acetyltransferase 2 is described. The most potent inhibitors

COMPOUNDS USEFUL AS HYPOGLYCEMIC AGENTS AND FOR TREATING ALZHEIMER'S DISEASE

-

, (2008/06/13)

Provided are methods for treating hyperglycemia and Alzheimer's disease utilizing certain rhodanine derivatives. Certain of the rhodanine derivatives utilized in the instant methods are novel and, accordingly, such compounds and pharmaceutical formulation

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