127813-30-3Relevant articles and documents
Multiple Roles of the Pyrimidyl Group in the Rhodium-Catalyzed Regioselective Synthesis and Functionalization of Indole-3-carboxylic Acid Esters
Jiang, Hui,Gao, Shang,Xu, Jinyi,Wu, Xiaoming,Lin, Aijun,Yao, Hequan
, p. 188 - 194 (2016)
A regioselective synthesis of indole-3-carboxylic acid esters from anilines and diazo compounds has been realized by making use of the pyrimidyl group-assisted rhodium-catalyzed C-H activation and C-N bond formation. The reaction proceeds under mild conditions, exhibits good functional group tolerance and scalability. Reutilization of the pyrimidyl directing group in the resulting products provided an efficient strategy for further C-7 functionalization of indoles. Moreover, the pyrimidyl moiety could be readily removed as a leaving group to offer various free N-H indoles.
Cp*IrIII-Catalyzed [3+2] Annulations of N-Aryl-2-aminopyrimidines with Sulfoxonium Ylides to Access 2-Alkyl Indoles Through C–H Bond Activation
Luo, Yi,Guo, Lingmei,Yu, Xinling,Ding, Haosheng,Wang, Huijing,Wu, Yong
supporting information, p. 3203 - 3207 (2019/06/08)
The iridium-catalyzed aromatic C–H alkylation followed by intramolecular annulation reactions between N-aryl-2-aminopyridines and sulfoxonium ylides for the synthesis of 2-alkyl indoles is described. This highly efficient and step-economical cyclization r
INTRAMOLECULAR DIELS-ALDER REACTIONS OF PYRIMIDINES: SYNTHESIS OF TRICYCLIC ANNELATED PYRIDINES.
Stolle, W. A. W.,Marcelis, A. T. M.,Koetsier, A.,Plas, H. C. van der
, p. 6511 - 6518 (2007/10/02)
2-(2-Trimethylsilylethynylphenyl-X)-pyrimidines (2, X=O, S, NAc, CH2, CO) easily undergo intramolecular Diels-Alder reaction with inverse electron demand, to give tricyclic annelated pyridines in excellent yields.The synthesis of 2 and the cycloaddition r