128230-83-1

Basic information

• Product Name: Cyclopropanecarbonyl chloride, 2-chloro-2-fluoro-1-methyl- (9CI)
• Synonyms: Cyclopropanecarbonyl chloride, 2-chloro-2-fluoro-1-methyl- (9CI)
• CAS NO: 128230-83-1
• Molecular Formula: C5H5Cl2FO
• Molecular Weight: 170.9970032
• Product Categories: ACIDHALIDE
• Mol File: 128230-83-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarbonyl chloride, 2-chloro-2-fluoro-1-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarbonyl chloride, 2-chloro-2-fluoro-1-methyl- (9CI)(128230-83-1)
• EPA Substance Registry System: Cyclopropanecarbonyl chloride, 2-chloro-2-fluoro-1-methyl- (9CI)(128230-83-1)

Safety Data

• Hazardous Substances Data: 128230-83-1(Hazardous Substances Data)

Upstream product

• 128230-79-5 2-fluoro-2-chloro-1-methyl-cyclopropane-carboxylic acid 

Relevant articles and documents

Fluorocyclopropyl derivative fungicide intermediates

Novel intermediates for fungicides, comprising fluorocyclopropyl derivatives of the formula STR1 in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl, X represents hydrogen, chlorine or bromine and R1 represents hydroxyl, alkoxy, alkyl or halogen.

Fluorinated cyclopropanecarboxylic acids and their derivatives

The addition of halofluorocarbenes such as :CF2, :CClF or :CBrF, generated from the appropriate halofluoromethanes with bases, to butadiene or isoprene gives the corresponding l-vinyl substituted halofluorocyclopropanes in moderate to good yield. The vinyl group facilitates the carbene addition and permits a subsequent wide derivatisation. Several transformations including hydroboration, oxidation and Curtius degradation are presented. Furthermore, replacement of the chlorine atom in 2-chloro-2-fluorocyclopropanecarboxylic acid derivatives by hydrogen is achieved catalytically with Raney nickel. This sequence provides a convenient route to mono-fluorine substituted cyclopropane carboxylic acids.