1286793-27-8

Basic information

• Product Name: (6-methylhept-5-en-3-yn-1-yl)benzene
• Synonyms: (6-methylhept-5-en-3-yn-1-yl)benzene
• CAS NO: 1286793-27-8
• Molecular Weight: 184.281
• Mol File: 1286793-27-8.mol

Chemical Properties

• CAS DataBase Reference: (6-methylhept-5-en-3-yn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (6-methylhept-5-en-3-yn-1-yl)benzene(1286793-27-8)
• EPA Substance Registry System: (6-methylhept-5-en-3-yn-1-yl)benzene(1286793-27-8)

Safety Data

• Hazardous Substances Data: 1286793-27-8(Hazardous Substances Data)

Upstream product

• 16520-62-0 4-Phenyl-1-butyne 
• 3017-69-4 2-methyl-1-propenylbromide 

Downstream Products

• 1286793-54-1 2-(6-methyl-1-phenylhepta-3,5-dien-3-yl)-(Z)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Rh(III)-catalyzed selective C7-H functionalization of indolines with 1,3-enynes enables access to six-membered 1,7-fused indolines

We described herein a Rh(III)-catalyzed C7-selective C–H activation/annulation of indolines with 1,3-enynes to efficiently access various privileged 1,7-fused indolines bearing an all-carbon quaternary stereogenic carbon center. Notably, the resulting pro

Catalytic 1,4-rhodium(III) migration enables 1,3-enynes to function as one-carbon oxidative annulation partners in C-H functionalizations

1,3-Enynes containing allylic hydrogens cis to the alkyne are shown to act as one-carbon partners, rather than two-carbon partners, in various rhodium-catalyzed oxidative annulations. The mechanism of these unexpected transformations is proposed to occur through double C-H activation, involving a hitherto rare example of the 1,4-migration of a RhIII species. This phenomenon is general across a variety of substrates, and provides a diverse range of heterocyclic products.

Regioselective Synthesis of 3-Hydroxy-4,5-alkyl-Substituted Pyridines Using 1,3-Enynes as Alkynes Surrogates

The poor regioselectivity of the [4 + 2] cycloaddition of 3-azetidinones with internal alkynes bearing two alkyl substituents via nickel-catalyzed carbon-carbon activation is addressed using 1,3-enynes as substrates. The judicious choice of substitution on the enyne enables complementary access to each regioisomer of 3-hydroxy-4,5-alkyl-substituted pyridines, which are important building blocks in medicinal chemistry endeavors.

Copper(i)-catalyzed regioselective monoborylation of 1,3-enynes with an internal triple bond: Selective synthesis of 1,3-dienylboronates and 3-alkynylboronates

Hooray for hydroboration! The products afforded by the title reaction depend on the substitution pattern on the double bond moiety of 1,3-enyne substrates (see scheme). These types of products, either 1,3-dienylboronates or 3-alkynylboronates, are difficult to obtain by other methods. Interestingly, ligand-controlled borylation was observed with high selectivity in some cases. pin=pinacolato, THF=tetrahydrofuran. Copyright