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128718-95-6

N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 128718-95-6 Structure

  • Basic information

    1. Product Name: N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester
    2. Synonyms: N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester
    3. CAS NO:128718-95-6
    4. Molecular Formula:
    5. Molecular Weight: 797.93
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 128718-95-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester(128718-95-6)
    11. EPA Substance Registry System: N-tert-butoxycarbonyl-D-p-nitrophenylalanyl-L-cysteinyl(Acm)-D-tryptophyl-L-leucine methyl ester(128718-95-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 128718-95-6(Hazardous Substances Data)

128718-95-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 128718-95-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,7,1 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 128718-95:
(8*1)+(7*2)+(6*8)+(5*7)+(4*1)+(3*8)+(2*9)+(1*5)=156
156 % 10 = 6
So 128718-95-6 is a valid CAS Registry Number.

128718-95-6Downstream Products

128718-95-6Relevant articles and documents

Novel Inhibitors of Human Renin Unrelated to the Angiotensinogen sequence. Analogues of a tetrapeptide, Boc-D-Cys(Acm)-D-Trp-Leu-OMe.

Dutta, Anand S,Cormley, James J,McLachlan, Peter F,Major, John S

, p. 101 - 170 (2007/10/02)

A protected tetrapeptide derivative, Boc-D-Phe-Cys(Acm)-D-Trp-Leu-OMe (1) was found to inhibit human renin (IC50 4E-5M).Further structure activity relationship studies based on 1 showed that the N-t-butoxycarbonyl and the methyl ester groups and the leucine residue were not critical for the renin inhibitory activity.Compounds with similar or improved potency could be made by various modifications of these residues.The other three amino-acid residues were much more important for activity.All the D-Trp substituted analogues were inactive.The Cys(Acm) residue could only be replaced by amino acid residues containing a basic group in the side-chain.With the exception of D-α-MePhe all the other substitutions in the D-Phe position gave compounds less potent than 1.

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