1287759-37-8Relevant articles and documents
Synthesis and antimicrobial properties of new mandelate ionic liquids
Wi?niewska, Anna,Lipiński, Piotr F.J.,Wo?niak, Krzysztof,Sanjuan-Szklarz, Fabiola W.,Cieniecka-Ros?onkiewicz, Anna,Michalczyk, Alicja,Dabrowski, Zbigniew,Kulig-Adamiak, Anna,Matalińska, Joanna,Le?, Andrzej,Cybulski, Jacek
, p. 705 - 715 (2016/08/06)
Novel mandelate ionic liquids with quaternary ammonium cations were synthesized and characterized. The compounds exhibit antimicrobial activity and the most potent one is of similar efficacy against Gram+ bacteria as its counterpart chloride. On the other hand, the mandelates are much less active against Gram- bacteria and fungi. QSAR models suggest that, with respect to cation, their potency depends on lipophilicity. The synthesized ionic liquids are also quite cytotoxic against mammalian cells.