128821-84-1Relevant articles and documents
Di[(R)-2-ethylhexyl] phthalate, a bioactive metabolite first isolated from three different bacillus species, and its synthesis
Castro, Miriam,Jiménez, Jacqueline,Ortiz, Aurelio,Sansinenea, Estibaliz
, p. 90 - 95 (2020/02/04)
Di(2-ethylhexyl) phthalate (DEHP) is the most common phthalate ester, which has been used as a plasticizer for the production of numerous polymers, particularly polyvinyl chloride (PVC). Many other groups have synthesized meso-DEHP indicating interest in this molecule, but we are the first to synthesize enantiomerically pure di[(R)-2-ethylhexyl] phthalate. We report herein, for the first time, the isolation-from the cultures of Bacillus thuringiensis, B. subtilis, and B. velezensis strains-of di[(R)-2-ethylhexyl] phthalate, enantiomerically pure and in good yields: its biological activity against bacteria and fungi was probed and for the first time its synthesis was done.
