129431-13-6Relevant articles and documents
DNA-Binding Compounds. III Synthesis of a Peptide-Linked Binuclear Platinum(II)-Terpyridine Complex
Bray, Andrew M.,Kelly, David P.,Mack, Philip O.-L.,Martin, Roger F.,Wakelin, Laurence P. G.
, p. 629 - 634 (2007/10/02)
A procedure has been developed for linking two terpyridineplatinum(II), Pt(tpy), chromophores by an oligopeptide chain.It relies on the use of a new reagent, succinimido 3-(triphenylmethylthio)propanoate (2), to acylate the amino end groups of an α,ω-diaminoalkane peptide.Subsequent deprotection of the sulfhydryl groups and coupling with IICl>Cl yields the binuclear complexes in good yields.This procedure allowed the synthesis of Cl2 (5b).
