130008-79-6

Basic information

• Product Name: rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol
• Synonyms: rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol
• CAS NO: 130008-79-6
• Molecular Formula: C20H24O4
• Molecular Weight: 328.40216
• Product Categories: Aromatics, Isotope Labelled Compounds, Miscellaneous Reagents
• Mol File: 130008-79-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol(130008-79-6)
• EPA Substance Registry System: rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol(130008-79-6)

Safety Data

• Hazardous Substances Data: 130008-79-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol is used as an intermediate in the synthesis of lignans, which are compounds with a wide range of biological activities. These lignans have potential applications in the development of new drugs and therapeutic agents, particularly for the treatment of various diseases and conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol serves as a key building block for the creation of more complex molecules and compounds. Its unique structure allows for the formation of various derivatives, which can be further utilized in different chemical reactions and processes.
Used in Research and Development:
rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol is also used in research and development settings, where scientists and researchers explore its properties and potential applications. rel-4-[(2R,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxyphenol can be employed in various studies to better understand its behavior and interactions with other molecules, leading to the discovery of new applications and uses.

Upstream product

• 124605-67-0 5-((2R,3R)-4-Benzo[1,3]dioxol-5-yl-2,3-dimethyl-butyl)-2-p-tolylsulfanylmethoxy-phenol 
• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 63057-72-7 2-benzyloxy-5-bromoanisole 
• 78919-28-5 (+)-chicanine 
• 55890-23-8 threo-austrobailignan-5 

Downstream Products

• 24150-24-1 terameprocol 

Relevant articles and documents

Synthesis of Lignans Based on a Borate-mediated One-pot Sequential Suzuki-Miyaura Coupling of Cyclic Boranes

Lignans are a group of polyphenolic phytochemicals that possess a large spectrum of chemical structures and biological activities. Here the syntheses of lignans – anwulignan, burseran, dehydroxycubebin, ruburisandrin B, and sesamin – are achieved based on a borate-mediated one-pot sequential Suzuki-Miyaura coupling of cis- and trans-fused bicyclic boranes, which were prepared by diastereoselective cyclic hydroboration of exo-cyclic diene with cyclopentyl- and thexylboranes, respectively. A one-pot sequential Suzuki-Miyaura coupling of each cyclic borate with various aryl bromides initiated by activation of the cyclic borane with the carbon nucleophile provided 2,3-dibenzylbutane derivatives with different aromatic substituents. Finally, the syntheses of naturally occurring lignans were accomplished in several steps from the products of Suzuki-Miyaura coupling.

Regioselective Cleavage of the Methylenedioxy Group: Conversion of (-)-Austrobailignan-5 to (-)-Dihydroguaiaretic Acid

A method for the selective cleavage of a benzodioxole (methylenedioxy group) to a methoxyphenol through the use of a p-methylthiophenoxide ion is described.When the procedure was applied to a lignan derivative such as (-)-austrobailignan-5, the reaction w

The structure of chicanine, a new lignan from Schisandra sp.

A new lignan, chicanine, isolated from the fruit of Schisandra sp., is shown to possess structure 1, 2S-(3-methoxy-4-hydroxyphenyl)-3R,4S-dimethyl-5S-(3,4-methylenedioxyphenyl)tetrahydrofuran, from spectra analysis and chemical conversions.The tetrahydrof