130081-94-6

Basic information

• Product Name: N-methyl-N-(2-propynyl)-2-(5-hydroxy-1-methylindolyl)methylamine
• Synonyms: N-methyl-N-(2-propynyl)-2-(5-hydroxy-1-methylindolyl)methylamine
• CAS NO: 130081-94-6
• Molecular Formula: C₁₄H₁₆N₂O
• Molecular Weight: 228.29
• Mol File: 130081-94-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 402.5°Cat760mmHg
• Flash Point: 197.2°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 4.7E-07mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: N-methyl-N-(2-propynyl)-2-(5-hydroxy-1-methylindolyl)methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(2-propynyl)-2-(5-hydroxy-1-methylindolyl)methylamine(130081-94-6)
• EPA Substance Registry System: N-methyl-N-(2-propynyl)-2-(5-hydroxy-1-methylindolyl)methylamine(130081-94-6)

Safety Data

• Hazardous Substances Data: 130081-94-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H16N2O/c1-4-7-15(2)10-12-8-11-9-13(17)5-6-14(11)16(12)3/h1,5-6,8-9,17H,7,10H2,2-3H3

Upstream product

• 91180-69-7 N-methyl-2-(5-methoxyindolyl)methylamine 
• 133845-54-2 5-benzyloxy-1-methyl-2-(methylaminomethyl)indole 
• 130081-92-4 1-methyl-2-((methylamino)methyl)-1H-indol-5-ol 
• 106-96-7 propargyl bromide 

Downstream Products

• 1334106-32-9 N-((5-((1-benzylpiperidin-4-yl)methoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine 
• 1334106-33-0 N-{[5-(2-(1-benzylpiperidin-4-yl)ethoxy)-1-methyl-1H-indol-2-yl]methyl}-N-methylprop-2-yn-1-amine 
• 1334106-31-8 N-((5-(3-(4-benzylpiperazine-1-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine 
• 1334106-30-7 N-{[5-(3-(4-benzylpiperidin-1-yl)propoxy)-1-methyl-1H-indol-2-yl]methyl}-N-methylprop-2-yn-1-amine 
• 1334106-29-4 N-{[5-(2-(4-benzylpiperidin-1-yl)ethoxy)-1-methyl-1H-indol-2-yl]methyl}-N-methylprop-2-yn-1-amine 
• 1334106-35-2 N-{[5-(4-(1-benzylpiperidin-4-yl)butoxy)-1-methyl-1H-indol-2-yl]methyl}-N-methylprop-2-yn-1-amine 
• 1334106-34-1 N-{[5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl]methyl}-N-methylprop-2-yn-1-amine 

Relevant articles and documents

Acetylenic and allenic derivatives of 2-(5-benzyloxyindolyl) and 2-(5-hydroxyindolyl)methylamines: synthesis and in vitro evaluation as monoamine oxidase inhibitors

We report the synthesis and in vitro studies as MAO inhibitors of 2 series of new acetylenic and allenic derivatives of 2-(5-benzyloxyindolyl)- and 2-(5-hydroxyindolyl)methylamines and their indolylmethylamine precursors.All compounds were MAO inhibitors and either did not show selectivity (the benzyloxy compounds 5) or were selective for MAO-A (most of the hydroxy compounds 7).Three of the studied compounds, 7d, 7g and 7i, were found to be slightly more selective for MAO-A than clorgyline.