13097-05-7

Basic information

• Product Name: 5-methoxy-3-phenyl-1H-indazole
• Synonyms: 5-methoxy-3-phenyl-1H-indazole
• CAS NO: 13097-05-7
• Molecular Weight: 224.262
• Mol File: 13097-05-7.mol

Chemical Properties

• CAS DataBase Reference: 5-methoxy-3-phenyl-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-3-phenyl-1H-indazole(13097-05-7)
• EPA Substance Registry System: 5-methoxy-3-phenyl-1H-indazole(13097-05-7)

Safety Data

• Hazardous Substances Data: 13097-05-7(Hazardous Substances Data)

Upstream product

• 17549-79-0 (2-amino-5-methoxyphenyl)(phenyl)methanone 
• 1597443-29-2 (2-amino-5-methoxyphenyl)phenylmethanone oxime 
• 104-94-9 4-methoxy-aniline 
• 1431709-08-8 4-(5-methoxy-3-phenyl-2H-indazol-2-yl)-2,6-dimethylphenol 
• 290368-03-5 tert-butyl 3-iodo-5-methoxy-1H-indazole-1-carboxylate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1239589-14-0 5-methoxy-3-phenyl-1-(pyridin-2-yl)-1H-indazole 
• 1575-18-4 5-methoxy-1,3-diphenyl-1H-indazole 
• 1239589-11-7 5-methoxy-1-(3-nitrophenyl)-3-phenyl-1H-indazole 
• 1222778-60-0 1-(4-fluorophenyl)-5-methoxy-3-phenyl-1H-indazole 
• 1222771-68-7 5-methoxy-1-(3-methoxyphenyl)-3-phenyl-1H-indazole 
• 1239589-12-8 5-methoxy-1-(2-methoxyphenyl)-3-phenyl-1H-indazole 
• 1222777-63-0 5-methoxy-3-phenyl-1-(p-tolyl)-1H-indazole 
• 1239589-06-0 5-methoxy-1-(4-methoxyphenyl)-3-phenyl-1H-indazole 
• 1239589-10-6 1-(3-fluorophenyl)-5-methoxy-3-phenyl-1H-indazole 
• 1239589-13-9 1-(2-fluorophenyl)-5-methoxy-3-phenyl-1H-indazole 
• 1239589-09-3 2-(5-methoxy-3-phenyl-1H-indazol-1-yl)aniline 
• 1239589-08-2 3-(5-methoxy-3-phenyl-1H-indazol-1-yl)aniline 
• 1239589-07-1 4-(5-methoxy-3-phenyl-1H-indazol-1-yl)aniline 

Relevant articles and documents

Mild method for the synthesis of 1H-indazoles through oxime-phosphonium ion intermediate

The synthesis of 1H-indazoles from o-aminobenzoximes is achieved via N-N bond formation using triphenylphosphine, I2, and imidazole. Selective formation of oxime-phosphonium ion intermediate in the presence of the amino group is the driving for

Rhodium(III)-catalyzed indazole synthesis by C-H bond functionalization and cyclative capture

An efficient, one-step, and highly functional group-compatible synthesis of substituted N-aryl-2H-indazoles is reported via the rhodium(III)-catalyzed C-H bond addition of azobenzenes to aldehydes. The regioselective coupling of unsymmetrical azobenzenes

ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans

The National Institutes of Health Molecular Libraries and Probe Production Centers Network (NIH-MLPCN) screened >300,000 compounds to evaluate their ability to restore fluconazole susceptibility in resistant Candida albicans isolates. Additional counter screens were incorporated to remove substances inherently toxic to either mammalian or fungal cells. A substituted indazole possessing the desired bioactivity profile was selected for further development, and initial investigation of structure-activity relationships led to the discovery of ML212.

Synthesis of 1,3-diarylsubstituted indazoles utilizing a Suzuki cross-coupling/deprotection/N-arylation sequence

Herein we report a general synthesis of 1,3-diarylsubstituted indazoles utilizing a two-step Suzuki crosscoupling/deprotection/N-arylation sequence. This procedure proceeds in excellent overall yield starting from the 3-iodo-N-Boc indazole derivative allowing for rapid access to these compounds.