1310572-82-7

Basic information

• Product Name: C₄₆H₇₅O₁₂P
• Synonyms: C₄₆H₇₅O₁₂P
• CAS NO: 1310572-82-7
• Molecular Weight: 851.068
• Mol File: 1310572-82-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₆H₇₅O₁₂P(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₆H₇₅O₁₂P(1310572-82-7)
• EPA Substance Registry System: C₄₆H₇₅O₁₂P(1310572-82-7)

Safety Data

• Hazardous Substances Data: 1310572-82-7(Hazardous Substances Data)

Upstream product

• 673500-71-5 C₃₄H₅₂O₈ 
• 75887-51-3 dihydroartemisinin acetate 
• 71939-50-9 dihydroartemisinin 
• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 
• 51672-37-8 dicyclohexyl phosphorochloridate 
• 673500-72-6 isobu-OH 

Relevant articles and documents

Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: A structure-activity study

We recently reported the anti-cancer and anti-cytomegalovirus (CMV) activity of artemisinin-derived trioxane diphenylphosphate dimer 838. To probe the relationship between chemical structure and anti-CMV and anti-cancer activities, we now report synthesis and evaluation of a series of eight new dimer phosphate ester analogs of 838. This series of novel molecules was screened against human foreskin fibroblasts (HFFs) infected with CMV and against the human Jurkat T cell acute lymphoblastic leukemia cell line. This SAR study confirms the very high anti-CMV and anti-cancer potencies of dimer diphenyl phosphate ester 838 without its being toxic to normal cells.