131088-03-4

Basic information

• Product Name: 2,4-dihydroxy-5-iodobenzaldehyde
• Synonyms: 2,4-dihydroxy-5-iodobenzaldehyde;Benzaldehyde, 2,4-dihydroxy-5-iodo-
• CAS NO: 131088-03-4
• Molecular Formula: C₇H₅IO₃
• Molecular Weight: 264.01727
• Mol File: 131088-03-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-dihydroxy-5-iodobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dihydroxy-5-iodobenzaldehyde(131088-03-4)
• EPA Substance Registry System: 2,4-dihydroxy-5-iodobenzaldehyde(131088-03-4)

Safety Data

• Hazardous Substances Data: 131088-03-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,4-dihydroxy-5-iodobenzaldehyde is used as a reagent in organic synthesis for the creation of different organic compounds. Its unique structure, which includes hydroxyl and iodine atoms, makes it a valuable intermediate in chemical reactions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,4-dihydroxy-5-iodobenzaldehyde is used as a starting material for the production of various pharmaceuticals. Its properties allow it to be a key component in the development of new drugs.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 2,4-dihydroxy-5-iodobenzaldehyde is employed as a starting material for the synthesis of various agrochemicals. Its moderate antibacterial and antifungal activities make it suitable for use in products designed to protect crops and enhance agricultural yields.
Used in Antibacterial and Antifungal Applications:
2,4-dihydroxy-5-iodobenzaldehyde is used as an active ingredient in antibacterial and antifungal products due to its reported moderate activities against these microorganisms, contributing to the development of treatments and preventive measures in both medical and agricultural contexts.

Upstream product

• 95-01-2 2,4-Dihydroxybenzaldehyde 

Downstream Products

• 1400807-67-1 2,4-bis(allyloxy)-5-iodobenzaldehyde 
• 1252581-54-6 6-hydroxy-2-(3,5-dihydroxyphenyl)benzofuran-5-carbaldehyde 

Relevant articles and documents

MOLECULES PRESENTING DUAL EMISSION PROPERTIES

The present invention concerns compound of formula (I): wherein: - A represents an electron-withdrawing group; - D represents an electron-donating group; - X is selected from the group consisting of: O, S and NR, wherein R is selected from the group consi

New synthetic method of natural product moracin Y

The present invention relates to a first and novel synthetic method of a moracin Y which is contained in mulberry leaves in an infinitesimal amount and exhibits an anticancer activity. The present invention includes a development of a novel synthetic method for efficiently synthesizing the moracin Y through three reaction stages which are a regioselective iodination, a sonogashira coupling, and a desilylation, starting from a 2,4-dihydroxybenzaldehyde which is a cheap compound.COPYRIGHT KIPO 2015

Facile synthesis of natural moracin compounds using PD(OAC)2/P(TBU)3-HBF4 as a sonogashira coupling reagent

An efficient and practical synthesis of natural moracins, which have diverse range of biological properties including anticancer, antioxidant, and antibacterial activities, has been achieved using Pd(OAc)2/P(tBu)3-HBF

Asymmetric total synthesis of smyrindiol employing an organocatalytic aldol key step

The first organocatalytic asymmetric synthesis of smyrindiol, by using an (S)-proline catalyzed enantioselective intramolecular aldol reaction as the key step, is described. Smyrindiol was synthesized from commercially available 2,4-dihydroxybenzaldehyde in 15 steps, with excellent stereoselectivity (de = 99%, ee = 99%). In the course of this total synthesis a new and mild coumarin assembly was developed.

The first total synthesis of moracin O and moracin P, and establishment of the absolute configuration of moracin O

The first total synthesis of the naturally occurring benzofurans, moracins O and P was achieved using a Sonogashira cross coupling reaction followed by in situ cyclization, and the absolute configuration of natural moracin O was established.