1313506-39-6Relevant articles and documents
Colorimetric detection of achiral anions and chiral carboxylates by a chiral thiourea-phthalimide dyad
Griesbeck, Axel G.,Hanft, Sebastian,Diaz Miara, Yrene
, p. 1385 - 1390 (2010)
The chiral chemosensor 1, based on a thiourea-activated phthalimide, is available by four reaction steps from 4-nitrophthalimide. 1 detects fluoride, chloride, acetate, and dihydrogen phosphate anions by changes in UV-vis absorption. Fluoride in excess induces deprotonation whereas the other anions show only complex formation in the ground state. 1H-NMR studies confirm the formation of these H-bonded complexes and the fluoride-induced receptor deprotonation in the recognition process. Moderate chiral recognition was observed for sodium d/l-lactate with Kass(d)/Kass(l) = 1.93.