131512-72-6

Basic information

• Product Name: 2-ethyl-5-phenyl-penta-2,4-dienoic acid
• Synonyms: 2-ethyl-5-phenyl-penta-2,4-dienoic acid
• CAS NO: 131512-72-6
• Molecular Weight: 202.253
• Mol File: 131512-72-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-ethyl-5-phenyl-penta-2,4-dienoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-5-phenyl-penta-2,4-dienoic acid(131512-72-6)
• EPA Substance Registry System: 2-ethyl-5-phenyl-penta-2,4-dienoic acid(131512-72-6)

Safety Data

• Hazardous Substances Data: 131512-72-6(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 127-09-3 sodium acetate 
• 141-75-3 butyryl chloride 
• 104-55-2 3-phenyl-propenal 
• 104-54-1 3-Phenylpropenol 
• 100-52-7 benzaldehyde 
• 103-26-4 methyl cinnamate 
• 106-31-0 butanoic acid anhydride 
• 100797-29-3 2-ethyl-5t-phenyl-pentadien-(2ξ.4)-al-(1) 

Relevant articles and documents

Highly Regio- A nd Enantioselective Hydrogenation of Conjugated α-Substituted Dienoic Acids

Highly regio- A nd enantioselective hydrogenation of conjugated α-substituted dienoic acids was realized for the first time using Trifer-Rh complex, providing a straightforward method for the synthesis of chiral α-substituted ?,?′-unsaturated acids. DFT calculations revealed N+H-O hydrogen bonding interaction is formed to stabilize the transition state and the coordination of 4,5-double bond to Rh(III) center would facilitate the reductive elimination process. This hydrogenation provided a gram-scale synthesis of the precursor of sacubitril.