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13187-90-1

H-ALA-GLU-OH, also known as L-alanyl-L-glutamic acid, is a dipeptide consisting of L-glutamic acid with an L-alanyl attached to its alpha-amino group. It is a white powder and is formed through a peptide bond between the carboxyl group of L-glutamic acid and the amino group of L-alanine.

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  • 13187-90-1 Structure

  • Basic information

    1. Product Name: H-ALA-GLU-OH
    2. Synonyms: L-ALANYL-L-GLUTAMIC ACID;H-ALA-GLU-OH;ALANINE GLUTAMATE;ALA-GLU;alanylglutamate;L-alanyl-glutamic acid;Ala-Glu-OH;Alanylglutamic acid
    3. CAS NO:13187-90-1
    4. Molecular Formula: C8H14N2O5
    5. Molecular Weight: 218.21
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 13187-90-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 520.5 °C at 760 mmHg
    3. Flash Point: 268.6 °C
    4. Appearance: /
    5. Density: 1.362 g/cm3
    6. Vapor Pressure: 3.12E-12mmHg at 25°C
    7. Refractive Index: 1.527
    8. Storage Temp.: -15°C
    9. Solubility: N/A
    10. PKA: 3.03±0.10(Predicted)
    11. CAS DataBase Reference: H-ALA-GLU-OH(CAS DataBase Reference)
    12. NIST Chemistry Reference: H-ALA-GLU-OH(13187-90-1)
    13. EPA Substance Registry System: H-ALA-GLU-OH(13187-90-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 13187-90-1(Hazardous Substances Data)

13187-90-1 Usage

Uses

Used in Pharmaceutical Industry:
H-ALA-GLU-OH is used as a building block for the enzymic production of oligopeptides, which are short chains of amino acids linked by peptide bonds. These oligopeptides have various applications in the pharmaceutical industry, including as therapeutic agents, drug delivery systems, and diagnostic tools.
Used in Biotechnology Industry:
In the biotechnology industry, H-ALA-GLU-OH is utilized in the enzymic production of human growth hormones. These hormones play a crucial role in regulating growth, cell reproduction, and cell regeneration in the human body. The use of H-ALA-GLU-OH in this process helps in the development of more effective and targeted treatments for growth-related disorders and conditions.
Used in Enzyme Research:
H-ALA-GLU-OH is also used as a substrate in enzyme research, particularly in the study of peptidases, which are enzymes that break down peptide bonds. This dipeptide serves as a model compound to investigate the mechanisms and specificity of these enzymes, contributing to a better understanding of their roles in various biological processes and potential applications in medicine and biotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 13187-90-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,8 and 7 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13187-90:
(7*1)+(6*3)+(5*1)+(4*8)+(3*7)+(2*9)+(1*0)=101
101 % 10 = 1
So 13187-90-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H14N2O5/c1-4(9)7(13)10-5(8(14)15)2-3-6(11)12/h4-5H,2-3,9H2,1H3,(H,10,13)(H,11,12)(H,14,15)/t4-,5-/m0/s1

13187-90-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name L-alanyl-L-glutamic acid

1.2 Other means of identification

Product number -
Other names H-Ala-Glu-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13187-90-1 SDS

13187-90-1Relevant articles and documents

Stereochemical aspects in the synthesis of novel N-(purin-6-yl)dipeptides as potential antimycobacterial agents

Musiyak, Vera V.,Nizova, Irina A.,Chulakov, Evgeny N.,Sadretdinova, Liliya Sh.,Tumashov, Andrey A.,Levit, Galina L.,Krasnov, Victor P.

, p. 407 - 415 (2021/02/26)

The synthesis of purine conjugates with natural amino acids is one of the promising directions in search for novel therapeutic agents, including antimycobacterial agents. The purpose of this study was to synthesize N-(purin-6-yl)dipeptides containing the

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