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131980-30-8

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131980-30-8 Usage

Chemical Properties

off-white to light yellow crystalline powder

Check Digit Verification of cas no

The CAS Registry Mumber 131980-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,9,8 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 131980-30:
(8*1)+(7*3)+(6*1)+(5*9)+(4*8)+(3*0)+(2*3)+(1*0)=118
118 % 10 = 8
So 131980-30-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H18N2O4/c1-15(2,3)21-14(20)17-12(13(18)19)8-10-5-4-6-11(7-10)9-16/h4-7,12H,8H2,1-3H3,(H,17,20)(H,18,19)/t12-/m1/s1

131980-30-8 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H62517)  N-Boc-3-cyano-L-phenylalanine, 95%   

  • 131980-30-8

  • 250mg

  • 635.0CNY

  • Detail
  • Alfa Aesar

  • (H62517)  N-Boc-3-cyano-L-phenylalanine, 95%   

  • 131980-30-8

  • 1g

  • 1905.0CNY

  • Detail
  • Aldrich

  • (14986)  Boc-Phe(3-CN)-OH  ≥98.0% (TLC)

  • 131980-30-8

  • 14986-1G

  • 3,006.90CNY

  • Detail

131980-30-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name BOC-L-3-CYANOPHENYLALANINE

1.2 Other means of identification

Product number -
Other names Boc-Phe(3-CN)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131980-30-8 SDS

131980-30-8Relevant articles and documents

A new strategy for the development of highly potent and selective plasmin inhibitors

Saupe, Sebastian M.,Steinmetzer, Torsten

supporting information; experimental part, p. 1171 - 1180 (2012/04/17)

A new structure-based strategy for the design of potent and selective plasmin inhibitors was developed. These compounds could be prepared by cyclizations between the P3 and P2 amino acid residues of substrate-analogue inhibitors using metathesis or a copper-catalyzed azide alkyne cycloaddition in combination with standard peptide couplings. The most potent bis-triazole derivative 10 inhibits plasmin and plasma kallikrein with Ki of 0.77 and 2.4 nM, respectively, whereas it has poor activity against the related trypsin-like serine proteases thrombin, factor Xa, or activated protein C. Modeling experiments revealed that inhibitor 10 adopts a compact and rigid structure that fits well into the relatively open active site of plasmin and plasma kallikrein, while it is rejected from sterically demanding residues present in loops of the other enzymes. These results from modeling confirm the selectivity profile found for inhibitor 10 in enzyme kinetic studies. Such compounds might be useful lead structures for the development of new antifibrinolytic drugs for use in cardiac surgery with cardiopulmonary bypass or organ transplantations to reduce bleeding complications.

N-sulphonylated amino acid derivatives, method for the production and use thereof

-

, (2008/06/13)

The present invention relates to N-sulfonylated amino acid derivatives, where an aryl radical is linked via the sulfonyl group N-terminally to the amino acid and a radical which comprises at least one imino group and at least one further basic group which

N-SULPHONYLATED AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF

-

Page/Page column 51, (2010/02/09)

The invention relates to N-sulphonylated amino acid derivatives wherein an aryl radical is bound to an amino acid via the sulphonyl groups in the N-terminal and a radical is bound in the C-terminal via the carbonyl group. Said radical contains at least one imino group and at least one other basic group representing an optionally modified amino-, amidino- or guanidino group. The invention also relates to a method for the production of said compounds and to the use thereof, especially as inhibitors of matriptase.

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