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132434-53-8

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132434-53-8 Usage

General Description

The chemical (2E)-1-(4-bromophenyl)-3-(furan-2-yl)prop-2-en-1-one, also known as chalcone, is an organic compound that consists of a substituted phenyl ring and a furan ring connected by a propenone linker. It is a yellow solid that is commonly used in organic synthesis and medicinal chemistry. Chalcone exhibits a wide range of biological activities, including antitumor, anti-inflammatory, and antioxidant properties. It is also used as a precursor in the synthesis of various natural and synthetic compounds. Its versatility and potential therapeutic applications make it a valuable chemical compound in pharmaceutical research and drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 132434-53-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,4,3 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 132434-53:
(8*1)+(7*3)+(6*2)+(5*4)+(4*3)+(3*4)+(2*5)+(1*3)=98
98 % 10 = 8
So 132434-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H9BrO2/c14-11-5-3-10(4-6-11)13(15)8-7-12-2-1-9-16-12/h1-9H/b8-7+

132434-53-8Relevant articles and documents

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Drake,Gilbert

, p. 4965 (1930)

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Novel 4,5-dihydro-1H-pyrazole derivatives as potential succinate dehydrogenase inhibitors: design, synthesis, crystal structure, biological activity and molecular modeling

Cheng, Wei,Jiang, Wenjing,Liu, Hui,Lu, Tong,Tang, Xiaorong,Wang, Jingwen,Xiao, Tingting,Zhang, Guilan,Zhang, Tingting

, (2021/10/05)

Twenty-eight new 4, 5-dihydro-1H-pyrazole derivatives were designed, synthesized and characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2j was characterized by single crystal X-ray diffraction. Their ant

Design, synthesis and insecticidal activity of novel semicarbazones and thiosemicarbazones derived from chalcone

Cheng, Wei,Xiao, Tingting,Qian, Weifeng,Lu, Tong,Zhang, Tingting,Tang, Xiaorong

, p. 3801 - 3809 (2020/03/23)

Thirty semicarbazone and thiosemicarbazone derivatives (2a–w and 4a–g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure o

Transition metal-free domino aryl-aryl coupling/phospha-Michael addition of diarylphosphinite to α,β-unsaturated ketones triggered by alkaline hydrolysis of (4-(2-alkenoyl)phenyl)triarylphosphonium salts

Huang, Wenhua,Xue, Jing-Yu

, (2021/11/08)

Alkaline hydrolysis of a variety of (4-(2-alkenoyl)phenyl)triarylphosphonium bromides is reported. This hydrolysis triggers coupling of 4-(2-alkenoyl)phenyl with one aryl via phosphorus(V). Both diarylphosphinite and an α,β-unsaturated ketone are in situ generated and then undergo phospha-Michael addition to provide β-diarylphosphoryl ketones bearing a biaryl moiety in 27–70% yields in the absence of a transition metal.

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