THIOFLAVINE S, also known as Direct Yellow 7, is a reagent with green light yellow color. It is soluble in water as a green fluorescent yellow and nearly colorless in strong sulfuric acid with blue fluorescence. THIOFLAVINE S is potentially useful as an amyloid plaque stain and is also used in the dyeing of cellulose fiber, wool, and silk.
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Basic information
- Product Name: THIOFLAVINE S
- Synonyms: thioflavine S practical grade;Methylated sulfonated primuline base;THIOFLAVINES,PRACTICAL;Direct yellow 7 (C.I. 49010);Direct Yellow7, ThioflavineS;[4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)phenyl]-dimethyl-amine chloride;ThioflavineS,Direct Yellow7;Amanil Brilliant Yellow S
- CAS NO:1326-12-1
- Molecular Formula: NULL
- Molecular Weight: 0
- EINECS: 215-418-0
- Product Categories: N/A
- Mol File: 1326-12-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
- Solubility: ethanol: water (1:1): soluble1mg/mL
- Stability: Light Sensitive
- CAS DataBase Reference: THIOFLAVINE S(CAS DataBase Reference)
- NIST Chemistry Reference: THIOFLAVINE S(1326-12-1)
- EPA Substance Registry System: THIOFLAVINE S(1326-12-1)
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Safety Data
- Hazard Codes: Xi
- Statements: 36/37/38
- Safety Statements: 26
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1326-12-1(Hazardous Substances Data)
1326-12-1 Usage
Uses
Used in Dye Industry:THIOFLAVINE S is used as a dye for cellulose fiber, wool, and silk dyeing. It is also used for silk printing and leather coloring. The dyeing process exhibits good levelness and exhaust dyeing properties.
Used in Staining Applications:
THIOFLAVINE S is used as an amyloid plaque stain, which is beneficial for identifying and studying these protein deposits in various research and diagnostic applications.
Standard:
The standard properties of THIOFLAVINE S include its resistance to acid and alkali, as well as its light fastness. The soaping and water fading properties are also important for its use in the dye industry. The ISO and AATCC ratings for these properties are as follows:
Acid Resistance: ISO 2-3, AATCC 3
Alkali Resistance: ISO 4, AATCC 2
Light Fastness: ISO 1, AATCC 1
Soaping: ISO 1-2, AATCC 2
Water Fading: Stain ISO 2, AATCC 2
These ratings indicate the performance and quality of THIOFLAVINE S in various conditions, making it a versatile and valuable reagent in both the dye and staining industries.
Preparation
(a) primrose spirit alkali (C.I.Direct Yellow 59, C.I. 49000) methylation, then will be preparing sulphonated product (GP 1251738); (b) primrose spirit alkali stlfonation, then will product methylation (GP 53333).Standard
Acid ResistanceFading
StainISO
2-3AATCC
3Check Digit Verification of cas no
The CAS Registry Mumber 1326-12-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,2 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1326-12:
(6*1)+(5*3)+(4*2)+(3*6)+(2*1)+(1*2)=51
51 % 10 = 1
So 1326-12-1 is a valid CAS Registry Number.
1326-12-1Upstream product
1326-12-1Downstream Products
1326-12-1Related news
Technical reportCombination of electron microscopy and the THIOFLAVINE S (cas 1326-12-1) technique in studies of the spinal cord microvasculature☆08/17/2019
The thioflavine S technique for delineating blood flow patterns in central nervous system tissue has been reviewed. Electron microscopic studies of the microvasculature of the feline spinal cord after intravascular administration of the thioflavine S demonstrated no fine structural alterations i...detailed
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THIOFLAVINE S
