13292-87-0Relevant articles and documents
Coyle, T. D.,Kaesz, H. D.,Stone, F. G. A.
, p. 2989 - 2994 (1959)
Reactions of pentaborane(11) with ethers
Kodama, Goji,Saturnino, Dennis J.
, p. 2243 - 2249 (1975)
Reactions of pentaborane(11) (B5H11) with ethers were studied at low temperatures by means of 11B NMR spectroscopy. The reactions of B5H11 with dimethyl and diethyl thioethers give the symmetrical cleavage products R2S·BH3 and R2S·B4H8. Species that are produced in the reaction system of B5H11 and oxoethers are very dependent upon the base strength of the ether. Strongly basic tetrahydrofuran can effect the unsymmetrical cleavage of B5H11 to produce H2B(THF)2+B4H9 -. Evidence for the formation of this cleavage product is based on the NMR spectral evidence and on the observed reaction products produced in the reaction of HCl with the B5H11-THF system. A second species is observable in the THF-B5H11 system which is more predominant at higher temperatures. This species is assigned as the simple adduct B5H11·THF. Moderately basic ethers like dimethyl and diethyl ethers produce only one observable species which is considered to be B5H11·OR2. Weakly basic diisopropyl ether does not react with B5H11. No direct evidence for the symmetrical cleavage of B5H11 by oxoethers has been observed. The similarities and differences between these reactions and analogous B4H10 reactions are discussed.
Coordination Chemistry of Borane in Solution: Application to a STING Agonist
Lemaire, Sébastien,Zhdanko, Alexander,van der Worp, Boris A.
, (2022/04/09)
Equilibrium constants were determined for ligand exchange reactions of borane complexes with various oxygen, sulfur, nitrogen, and phosphorus nucleophiles in solution, and a binding affinity scale was built spanning a range of 12 orders of magnitude. While the Keq are minimally dependent on the solvent, the rate of ligand exchange varies significantly. The fastest and slowest rates were observed in THF and CDCl3, respectively. Moreover, the ligand exchange rate differs in a very broad range depending on stability of the starting complex. Binding of BH3 was found to be much more sensitive to steric factors than protonation. Comparing nitrogen bases having equal steric properties, a linear correlation of BH3 binding affinity vs. Br?nsted acidity was found. This correlation can be used to quickly estimate the BH3 binding affinity of a substrate if pKa is known. Kinetic studies suggest the ligand exchange to occur as a bimolecular SN2 reaction unless other nucleophilic species were present in the reaction mixture.
Stabilizer-containing borane reagent combination solution, and preparation method and use thereof
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Paragraph 0035-0036, (2018/06/04)
The invention provides a stabilizer-containing borane reagent combination solution. The borane reagent combination solution comprises a borane-dimethyl sulfide complex, tetrahydrofuran and a stabilizer, wherein the concentration of the borane-dimethyl sulfide complex in tetrahydrofuran is 1-10 mol/L, and a molar ratio of the borane-dimethyl sulfide complex to the stabilizer is 100:1 to 1000:1. Thecombination solution has the advantages of high concentration, good thermal stability, realization of high-efficiency utilization of a reaction container, and saving of the tetrahydrofuran reagent toreduce the cost; and the combination solution achieves a good reaction enantioselectivity and a high enantiomeric excess value (% ee) of a product when applied to Corey asymmetric reduction.
Synthesis of nido-B11H14- and alkyl derivatives via systematic cage enlargement of the decaborane(14) system: Crystal structure of 7-Thx-B11H13-
Gaines, Donald F.,Bridges, Adam N.,Hayashi, Randy K.
, p. 1243 - 1244 (2008/10/08)
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