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N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is a chemical compound that is a derivative of L-lysine, modified with pentafluorophenyl ester and fluorenylmethyloxycarbonyl (Fmoc) protecting groups. It is widely used in the field of bioconjugation and peptide chemistry due to its unique structure and reactivity, making it a valuable tool in the development of peptide-based drugs, diagnostics, and biomaterials.

132990-14-8

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132990-14-8 Usage

Uses

Used in Bioconjugation:
N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is used as a coupling agent in bioconjugation for the formation of covalent bonds between biomolecules, such as proteins, peptides, and other ligands. Its reactivity allows for efficient and specific conjugation, enabling the development of novel bioconjugates with improved properties and functions.
Used in Peptide Synthesis:
In the field of peptide chemistry, N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester serves as a building block for the synthesis of peptide-based materials. Its Fmoc protecting group allows for selective deprotection and coupling during solid-phase peptide synthesis, facilitating the assembly of complex peptide sequences with high purity and yield.
Used in Protein Labeling:
N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is used as a labeling agent for the modification of proteins with various functional groups, such as fluorescent dyes, affinity tags, or bioactive molecules. This allows for the tracking, detection, and manipulation of proteins in biological systems, providing valuable insights into their structure, function, and interactions.
Used in Drug Development:
In the pharmaceutical industry, N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is utilized in the development of peptide-based drugs. Its unique structure and reactivity enable the design and synthesis of therapeutic peptides with specific biological activities, such as enzyme inhibitors, receptor agonists or antagonists, and immunomodulatory agents.
Used in Diagnostics:
N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is employed in the development of diagnostic tools, such as immunoassays and biosensors, by conjugating specific recognition elements, like antibodies or aptamers, to detection platforms. This allows for the sensitive and selective detection of target analytes, including proteins, nucleic acids, and small molecules, in various biological samples.
Used in Biomaterials:
In the field of biomaterials, N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester is used for the functionalization of materials with bioactive peptides or proteins. This enables the creation of biocompatible and responsive materials for applications in tissue engineering, drug delivery, and medical devices, improving their performance and biointegration with biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 132990-14-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,9,9 and 0 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 132990-14:
(8*1)+(7*3)+(6*2)+(5*9)+(4*9)+(3*0)+(2*1)+(1*4)=128
128 % 10 = 8
So 132990-14-8 is a valid CAS Registry Number.
InChI:InChI=1/C42H33F5N2O6/c43-34-35(44)37(46)39(38(47)36(34)45)55-40(50)33(49-42(52)54-22-32-29-17-7-3-13-25(29)26-14-4-8-18-30(26)32)19-9-10-20-48-41(51)53-21-31-27-15-5-1-11-23(27)24-12-2-6-16-28(24)31/h1-8,11-18,31-33H,9-10,19-22H2,(H,48,51)(H,49,52)/t33-/m0/s1

132990-14-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,3,4,5,6-pentafluorophenyl) (2S)-2,6-bis(9H-fluoren-9-ylmethoxycarbonylamino)hexanoate

1.2 Other means of identification

Product number -
Other names Fmoc-Lys(Fmoc)-Opfp

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132990-14-8 SDS

132990-14-8Upstream product

132990-14-8Downstream Products

132990-14-8Relevant articles and documents

A process for preparing an antigenic or immunogenic conjugate as well as the use of such conjugates

-

, (2008/06/13)

The invention relates to a process for preparing an antigenic or immunogenic conjugate such as a multiple antigenic peptide system. A branched structure based on amino acids such as lysine is reacted with an antigenic or immunogenic compound. Preferably said compound is coupled to a residue containing the 3-nitro-2-pyridine sulfenyl group. The conjugates obtainable according to this process are used for the preparation of pharmaceutical products.

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