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CAS

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133522-39-1

(R)-1-Amino-3-phenyl-2-propanol, also known as (R)-norephedrine, is a chiral chemical compound with the molecular formula C9H13NO. It is an enantiomer of the sympathomimetic amine norephedrine and possesses a chiral center. The (R)-enantiomer has been found to exhibit various pharmaceutical properties, making it a valuable compound in the development of pharmaceutical drugs.

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  • 133522-39-1 Structure

  • Basic information

    1. Product Name: (R)-1-Amino-3-phenyl-2-propanol
    2. Synonyms: (R)-1-Amino-3-phenyl-2-propanol;(R)-1-Amino-3-phenylpropan-2-ol
    3. CAS NO:133522-39-1
    4. Molecular Formula: C9H13NO
    5. Molecular Weight: 151.20562
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 133522-39-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-1-Amino-3-phenyl-2-propanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-1-Amino-3-phenyl-2-propanol(133522-39-1)
    11. EPA Substance Registry System: (R)-1-Amino-3-phenyl-2-propanol(133522-39-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133522-39-1(Hazardous Substances Data)

133522-39-1 Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-Amino-3-phenyl-2-propanol is used as an intermediate in the synthesis of pharmaceutical drugs such as ephedrine and pseudoephedrine. These drugs have various applications, including the treatment of respiratory conditions, nasal congestion, and as stimulants.
Used in Respiratory Applications:
(R)-1-Amino-3-phenyl-2-propanol is used as a bronchodilator for the treatment of respiratory conditions. Its bronchodilating properties help to relax and widen the airways, making it easier for individuals to breathe.
Used as a Stimulant:
(R)-1-Amino-3-phenyl-2-propanol is used as a stimulant due to its sympathomimetic properties. It can increase alertness, focus, and energy levels, making it useful in various applications where increased mental and physical performance is desired.
Due to its stereochemistry, (R)-1-Amino-3-phenyl-2-propanol has different pharmacological effects compared to its (S)-enantiomer, making it a valuable compound for targeted drug development and therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 133522-39-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,5,2 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 133522-39:
(8*1)+(7*3)+(6*3)+(5*5)+(4*2)+(3*2)+(2*3)+(1*9)=101
101 % 10 = 1
So 133522-39-1 is a valid CAS Registry Number.

133522-39-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-1-amino-3-phenylpropan-2-ol

1.2 Other means of identification

Product number -
Other names (R)-1-Amino-3-phenylpropan-2-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133522-39-1 SDS

133522-39-1Downstream Products

133522-39-1Relevant articles and documents

An alternate synthesis of appetite suppressant (R)-2-benzylmorpholine employing Sharpless asymmetric epoxidation strategy

Viswanadh,Mujumdar,Sasikumar,Kunte,Muthukrishnan

, p. 861 - 863 (2016/02/05)

An alternate synthesis of (R)-2-benzylmorpholine 1, an appetite suppressant agent has been accomplished starting from readily available trans-cinnamyl alcohol employing Sharpless asymmetric epoxidation strategy as a key step, with an overall yield of 24%.

Isoquinolines useful as analgesics

-

, (2008/06/13)

PCT No. PCT/SE97/00315 Sec. 371 Date Oct. 6, 1997 Sec. 102(e) Date Oct. 6, 1997 PCT Filed Feb. 25, 1997 PCT Pub. No. WO97/31940 PCT Pub. Date Sep. 4, 1997The present invention is directed to compounds that act as analgesics and that have the structure of

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